Abstract：
Through an ex vivo experimental study, we aimed to compare the effects of the Ho: YAG laser Virtual Basket (VB™) modulation and a Thulium fiber laser (TFL) on kidney tissue in different environments and using laser configurations. The 100 W Ho: YAG (Cyber Ho, Quanta System, Italy) and 60 W TFL (Fiber Dust, Quanta System, Italy) laser devices were used. The following laser settings were selected: power in the range of 10-60 W, frequency of 20-40 Hz, and energy of 0.5-1-1.5 J. A medium pulse duration of 600 µsec was used for VB™, while short (spdTFL; 50 µsec) and long (lpdTFL; 15,000 µsec) were used for TFL. The tissue\'s incision depth (ID), vaporization area (VA), coagulation area (CA), total laser area (TLA = VA + CA), surface section (SS), and lateral effect (LE) were measured. In total, 108 experiments were conducted. No statistically significant difference in mean VA, TLA, ID, LE, or SS was observed between VB™, spdTFL, and lpdTFL in the low-power output group in saline (p > 0.05). However, the mean CA was statistically significantly higher for VB™ (p = 0.005). In saline and high-power output group, the mean VA, CA, TLA, LE, and ID were higher when using lpdTFL than other pulse durations (p = 0.001, p = 0.001, p = 0.001, p = 0.006, and p = 0.001, respectively). Similar to lpdTFL, VB™ may provide controlled dissection and incision as well as haemostasis. At different laser settings, the individual effects of laser properties (such as pulse length, energy and frequency) on tissue may be more significant.
摘要：
通过离体实验研究，我们旨在比较Ho:YAG激光虚拟篮(VB™)调制和Thulium光纤激光器(TFL)在不同环境和使用激光配置对肾脏组织的影响.100WHo：YAG(CyberHo，Quanta系统,意大利）和60WTFL（纤维粉尘，Quanta系统,意大利)使用了激光设备。选择了以下激光器设置：功率在10-60W范围内，频率为20-40Hz，能量为0.5-1-1.5J。VB™使用600微秒的中等脉冲持续时间，而短（spdTFL;50µsec）和长（lpdTFL;15,000µsec）用于TFL。组织的切口深度(ID),汽化面积(VA),凝血面积（CA），激光总面积（TLA=VA+CA），表面截面(SS),测量横向效应(LE)。总的来说,进行了108次实验。平均VA无统计学差异，TLA,ID,LE,或SS在VB™之间观察到，spdTFL,低功率输出组在生理盐水中的lpdTFL（p>0.05）。然而,VB™的平均CA在统计学上显著较高(p=0.005).在盐水和高功率输出组中，平均VA，CA,TLA,LE,使用lpdTFL时,和ID高于其他脉冲持续时间(分别为p=0.001,p=0.001,p=0.001,p=0.006和p=0.001)。类似于lpdTFL,VB™可以提供受控的解剖和切口以及止血。在不同的激光设置下，激光特性的个别影响(如脉冲长度，能量和频率)对组织的影响可能更显著。
