Abstract：
Anal squamous cell carcinoma, typically associated with human papillomavirus infection, remains a rare malignancy. This article outlines a case of local recurrence in a male patient with a history of HIV and hepatitis C virus infection, previously treated with chemoradiotherapy. Extensive tumour involvement called for total pelvic exenteration extended to anterior osteomuscular compartment and genitalia. The surgical approach involved multidisciplinary collaboration and detailed preoperative planning using three-dimensional reconstruction. Key surgical considerations comprised the following: achieving tumour-free margins (R0 resection), extensive osteotomies and intricate pelvic floor reconstruction with prosthetic mesh and flap reconstruction. The procedure successfully yielded an R0 resection, maintaining adequate lower limb functionality. Our case report underscores the benefits of pelvic exenteration in locally advanced or recurrent pelvic tumours, invariably following careful patient selection and exhaustive preoperative studies.
摘要：
肛门鳞状细胞癌，通常与人乳头瘤病毒感染有关，仍然是一种罕见的恶性肿瘤.本文概述了一例有HIV和丙型肝炎病毒感染史的男性患者局部复发的病例,以前接受过放化疗。广泛的肿瘤受累，要求进行全盆腔切除术，延伸到骨膜前室和生殖器。手术方法涉及多学科合作和使用三维重建的详细术前计划。主要的手术考虑因素包括：实现无瘤切缘（R0切除），广泛的截骨术和复杂的盆底重建与假体网状和皮瓣重建。手术成功切除了R0,维持足够的下肢功能。我们的病例报告强调了在局部晚期或复发性盆腔肿瘤中盆腔切除术的益处。总是经过仔细的患者选择和详尽的术前研究。
