关键词: DNA database DNA profiling Forensic evidence Sexual assault Statistical interpretation

Mesh : Humans India DNA Fingerprinting / methods Specimen Handling / methods Databases, Nucleic Acid Genetic Markers Forensic Genetics / methods DNA / analysis

来  源:   DOI:10.1016/j.scijus.2024.05.003

Abstract:
DNA technology is the gold standard with respect to the identification of individuals from biological evidence. The technology offers the convenience of a universally similar approach and methodology for analysis across the globe. However, the technology has not realised its full potential in India due to the lack of a DNA database and lacunae in sample collection and preservation from the scene of crime and victims (especially those of sexual assault). Further, statistical interpretation of DNA results is non-existent in the majority of cases. Though the latest technologies and developments in the field of DNA analysis are being adopted and implemented,very little has been enacted practically to improve optimise sample collection and preservation. This article discusses current casework scenarios that highlight the pitfalls and ambiguous areas in the field of DNA analysis, especially with respect DNA databases, sampling, andstatistical approaches to genetic data analysis. Possible solutions and mitigation measures are suggested.
摘要:
DNA技术是从生物学证据中识别个体的金标准。该技术为全球分析提供了普遍相似的方法和方法的便利。然而,由于缺乏DNA数据库以及在犯罪现场和受害者(尤其是性侵犯的受害者)的样本收集和保存方面的空白,该技术尚未在印度充分发挥其潜力。Further,在大多数情况下,DNA结果的统计解释是不存在的。尽管DNA分析领域的最新技术和发展正在被采用和实施,几乎没有制定任何措施来改善优化样品收集和保存。本文讨论了当前的案例工作场景,这些场景突出了DNA分析领域的陷阱和模糊区域,特别是在DNA数据库方面,采样,遗传数据分析的统计方法。提出了可能的解决方案和缓解措施。
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