[Box: see text].
[方框:见正文]。
KCTD8 的表观遗传沉默通过激活 PI3K / AKT 信号促进肝细胞癌生长。
关键词: DNA methylation KCTD8 PI3K/AKT signaling pathway hepatocellular carcinoma tumor suppressor
Mesh : Humans Carcinoma, Hepatocellular / genetics pathology metabolism Liver Neoplasms / genetics pathology metabolism Proto-Oncogene Proteins c-akt / metabolism Phosphatidylinositol 3-Kinases / metabolism Animals DNA Methylation Epigenesis, Genetic Signal Transduction Mice Cell Line, Tumor Female Male Gene Expression Regulation, Neoplastic Gene Silencing Cell Proliferation Middle Aged Mice, Nude Prognosis
来 源:
DOI:10.1080/17501911.2024.2370590
PDF(Pubmed)