Abstract：
BACKGROUND: Nasopharyngeal carcinoma (NPC) mortality varies based on multiple risk factors. While NPC mortality is higher in Asia, little is known about Asian subgroups in the United States (US).
METHODS: Using the 2005-2020 National Vital Statistics System, we examined NPC mortality by age, race (non-Hispanic black, Hispanic white (HW), non-Hispanic white (NHW), Chinese, Filipino, Asian Indian, Japanese, Korean, Vietnamese), sex, and nativity (Untied States or foreign-born).
RESULTS: Upon disaggregation, Chinese (1.96 [CI: 1.78-2.16]), Filipino (0.68 [0.68-1.11]), and Vietnamese Americans (0.68 [0.52-1.10]) had the top age-adjusted mortality rates (AAMR per 100 000 person-years). Foreign-born Chinese, Vietnamese, Filipinos, Asian Indians, and NHW had higher AAMRs compared to US-born persons. All male groups had higher AAMR compared to females. Stratifying for race, nativity, and sex, foreign-born Chinese males (4.09 [3.79-4.40]) had the highest AAMR.
CONCLUSIONS: These findings demonstrate the importance of disaggregating NPC mortality data by Asian subgroups, providing valuable insights for targeted public health interventions in the United States.
METHODS: Using the 2005-2020 National Vital Statistics System, we examined NPC mortality by age, race (non-Hispanic black, Hispanic white (HW), non-Hispanic white (NHW), Chinese, Filipino, Asian Indian, Japanese, Korean, Vietnamese), sex, and nativity (Untied States or foreign-born).
RESULTS: Upon disaggregation, Chinese (1.96 [CI: 1.78-2.16]), Filipino (0.68 [0.68-1.11]), and Vietnamese Americans (0.68 [0.52-1.10]) had the top age-adjusted mortality rates (AAMR per 100 000 person-years). Foreign-born Chinese, Vietnamese, Filipinos, Asian Indians, and NHW had higher AAMRs compared to US-born persons. All male groups had higher AAMR compared to females. Stratifying for race, nativity, and sex, foreign-born Chinese males (4.09 [3.79-4.40]) had the highest AAMR.
CONCLUSIONS: These findings demonstrate the importance of disaggregating NPC mortality data by Asian subgroups, providing valuable insights for targeted public health interventions in the United States.
摘要：
背景：鼻咽癌（NPC）死亡率因多种危险因素而异。虽然亚洲的NPC死亡率较高，对美国(US)的亚洲分组知之甚少。
方法：使用2005-2020年国家生命统计系统，我们按年龄检查了NPC死亡率，种族(非西班牙裔黑人，西班牙裔白人（HW），非西班牙裔白人（NHW），中文,菲律宾人,亚洲印第安人,日本人,韩语,越南语),性别,和诞生（美国或外国出生）。
结果：分解后，中文（1.96[CI：1.78-2.16]），菲律宾人（0.68[0.68-1.11]），和越南裔美国人(0.68[0.52-1.10])的年龄调整死亡率最高(AAMR每10万人年).外国出生的中国人，越南人,菲律宾人,亚洲印第安人,与美国出生的人相比，NHW的AAMR更高。所有男性组的AAMR均高于女性。种族分层，耶稣诞生,和性,外国出生的中国男性（4.09[3.79-4.40]）的AAMR最高。
结论：这些发现证明了按亚洲亚组分类NPC死亡率数据的重要性，为美国有针对性的公共卫生干预提供有价值的见解。
方法：使用2005-2020年国家生命统计系统，我们按年龄检查了NPC死亡率，种族(非西班牙裔黑人，西班牙裔白人（HW），非西班牙裔白人（NHW），中文,菲律宾人,亚洲印第安人,日本人,韩语,越南语),性别,和诞生（美国或外国出生）。
结果：分解后，中文（1.96[CI：1.78-2.16]），菲律宾人（0.68[0.68-1.11]），和越南裔美国人(0.68[0.52-1.10])的年龄调整死亡率最高(AAMR每10万人年).外国出生的中国人，越南人,菲律宾人,亚洲印第安人,与美国出生的人相比，NHW的AAMR更高。所有男性组的AAMR均高于女性。种族分层，耶稣诞生,和性,外国出生的中国男性（4.09[3.79-4.40]）的AAMR最高。
结论：这些发现证明了按亚洲亚组分类NPC死亡率数据的重要性，为美国有针对性的公共卫生干预提供有价值的见解。
