PDF(Pubmed)
Abstract：
Neurosarcoidosis is a rare manifestation of sarcoidosis, posing diagnostic challenges due to its varied clinical presentation and the lack of definitive diagnostic tests. We present a case of a 46-year-old African American female with progressive ascending bilateral sensory loss, weakness, and a bifrontal headache. Despite undergoing extensive diagnostic workup including cerebrospinal fluid analysis, neuroimaging, and bronchoscopic evaluation, a definitive diagnosis remained elusive. The patient underwent an open cervical spinal cord biopsy, which did not yield conclusive evidence of neurosarcoidosis. Subsequent complications included suspicion of an epidural abscess and post-operative cervical kyphosis. This case underscores the diagnostic dilemma and potential complications associated with the evaluation and management of neurosarcoidosis, highlighting the importance of a multidisciplinary approach in such cases.
摘要：
神经结节病是结节病的罕见表现，由于其临床表现多样和缺乏明确的诊断测试，构成了诊断挑战。我们介绍了一例46岁的非洲裔美国女性，双侧感觉丧失进行性上升，弱点,和双额骨头痛。尽管接受了广泛的诊断检查，包括脑脊液分析，神经影像学,和支气管镜评估，明确的诊断仍然难以捉摸。患者接受了开放式颈脊髓活检，这并没有产生神经结节病的确凿证据。随后的并发症包括怀疑硬膜外脓肿和术后颈椎后凸。该病例强调了与神经结节病的评估和治疗相关的诊断困境和潜在并发症。强调在这种情况下采取多学科方法的重要性。
