UNASSIGNED: Weighted logistic regression and subgroup analyses were used to investigate the association between arthritis incidence and ED among participants in the 2001-2004 National Health and Nutrition Examination Survey database.
UNASSIGNED: Among the participants, 27.8% and 18.5% had a self-reported history of ED and arthritis, respectively. ED was associated with arthritis (odds ratio [OR]=4.00; 95% confidence interval [CI]: 3.20-4.99; p<0.001], which remained significant after adjustment (OR=1.42, 95% CI: 1.00-1.96; p<0.001). Stratified by type of arthritis, after full adjustment, osteoarthritis remained significant (OR=1.11; 95% CI: 1.03-1.20; p=0.017), and rheumatoid arthritis (OR=1.03, 95% CI: 0.93-1.13; p= 0.5) and other arthritis (OR=1.04, 95% CI: 0.98-1.11; p=0.2) were not significantly correlated with ED. Multiple inference analyses confirmed the robustness of the results.
UNASSIGNED: Our study showed that arthritis was strongly associated with ED. There is an urgent need to raise awareness and conduct additional research on the reasons behind this association in order to implement more scientific and rational treatment programs for patients with ED and arthritis.
在2001-2004年国家健康和营养调查数据库中,使用加权逻辑回归和亚组分析来调查关节炎发病率与ED之间的关联。
■在参与者中,27.8%和18.5%有自我报告的ED和关节炎史,分别。ED与关节炎相关(比值比[OR]=4.00;95%置信区间[CI]:3.20-4.99;p<0.001],校正后仍然显著(OR=1.42,95%CI:1.00-1.96;p<0.001)。按关节炎类型分层,经过充分调整,骨关节炎仍然显著(OR=1.11;95%CI:1.03-1.20;p=0.017),和类风湿关节炎(OR=1.03,95%CI:0.93-1.13;p=0.5)和其他关节炎(OR=1.04,95%CI:0.98-1.11;p=0.2)与ED无显著相关性。多重推断分析证实了结果的稳健性。
■我们的研究表明关节炎与ED密切相关。迫切需要提高认识并对这种关联背后的原因进行更多研究,以便为ED和关节炎患者实施更科学,合理的治疗计划。