UNASSIGNED: We conducted a decentralized randomized controlled trial where participants (n = 40) with symptomatic knee OA were randomized into mindful exercise (n = 21) or exercise-only (n = 19) groups. Both groups received supervised group-based interventions weekly for 8-weeks via Zoom. Primary outcomes were safety, fidelity, and feasibility of the mindful exercise intervention. Participants completed patient-reported outcomes (PRO) for pain, function, and psychological measures at baseline, week-8, and week-14.
UNASSIGNED: Participants were from 21 US states; >90% identified as having White race, 16% were from rural areas, and approximately 40% had an annual income < $50,000. At 8-weeks, mindful exercise and exercise groups had retention rates of 86% (18/21) and 100% (19/19), and attendance was 54% (11.4/21) and 68% (13/19) respectively. There were no adverse events in the mindful exercise group and four in the exercise group related to exacerbation of knee pain. Preliminary findings showed numerically larger improvements in several PROs for the mindful exercise group.
UNASSIGNED: An 8-week telehealth, group-based, mindful exercise intervention was safe for people with knee OA. Our decentralized approach was feasible in terms of recruitment and retention. Further refinement is needed to improve intervention attendance and participant diversity.
■我们进行了一项分散的随机对照试验,其中有症状的膝关节OA的参与者(n=40)被随机分为正念运动组(n=21)或仅运动组(n=19)。两组均通过Zoom每周接受基于小组的有监督干预,为期8周。主要结果是安全性,保真度,以及正念运动干预的可行性。参与者完成了患者报告的疼痛结果(PRO),函数,和基线时的心理测量,第8周和第14周。
■参与者来自美国21个州;>90%被确定为白人种族,16%来自农村地区,大约40%的人年收入<5万美元。在8周的时候,正念运动和运动组的保留率为86%(18/21)和100%(19/19),出勤率分别为54%(11.4/21)和68%(13/19)。正念运动组没有发生与膝关节疼痛加重相关的不良事件,运动组中有4例。初步发现显示,正念运动组的几个PRO的改善幅度更大。
■为期8周的远程医疗,基于群体,正念运动干预对膝关节OA患者是安全的。我们的分散方法在征聘和留用方面是可行的。需要进一步改进,以提高干预出勤率和参与者多样性。