PDF(Pubmed)
Abstract：
Discordant lymphoma (DL) is an uncommon condition in which two or more histologically different types of lymphomas are present at distinct anatomical sites in the same patient. Here, we report a case of a pediatric patient under 10 years old presenting with symptoms of general sickness with cervical lymphadenopathy, abdominal distension and an abdominal mass. Upon conducting investigations, classic Hodgkin lymphoma (CHL) was detected in the cervical lymph nodes, and high-grade B-cell non-Hodgkin lymphoma was detected in the bone marrow and abdominal mass. The patient was therefore diagnosed with DL. The boy was initially diagnosed with CHL but proceeded to have aggressive disease progression, due to which further workup was done. In the past, literature reports have been published for adult cases of DL, and currently, research is being conducted to formulate treatment protocols for it. However pediatric cases of DL remain widely undiscussed. Since we are dealing with a rare or widely underreported condition, we found it significant to elaborate on its clinical presentation, treatment plan, complications and prognosis.
摘要：
不和谐淋巴瘤（DL）是一种罕见的疾病，其中同一患者的不同解剖部位存在两种或多种组织学上不同类型的淋巴瘤。这里,我们报告了一例10岁以下的儿科患者，表现为一般疾病伴颈部淋巴结肿大的症状，腹胀和腹部肿块。在进行调查时，在颈部淋巴结中检测到经典霍奇金淋巴瘤（CHL），在骨髓和腹部肿块中检测到高级别B细胞非霍奇金淋巴瘤。因此,患者被诊断患有DL。该男孩最初被诊断出患有CHL，但随后出现了侵袭性疾病进展，因此做了进一步的工作。在过去,已经发表了成人DL病例的文献报告，目前,正在进行研究以制定治疗方案。然而，DL的儿科病例仍未被广泛讨论。由于我们正在处理一种罕见或广泛低估的情况，我们发现详细阐述它的临床表现很重要，治疗计划,并发症和预后。
