关键词: COVID‐19 infection dry eye dry mouth sequela sicca syndrome

来  源:   DOI:10.1002/ccr3.9177   PDF(Pubmed)

Abstract:
Several reports of suspected oral and ocular manifestations of coronavirus disease 2019 (COVID-19) has prompted investigations into ocular signs, symptoms, and transmission (5).11.2% of patients with COV19 infection had ocular symptoms, including ocular pain, conjunctivitis, dry eye, and floaters, meanwhile, many studies had documented oral symptoms such as dry mouth and dysgeusia in these patients. Our case reported a 39-year-old male, presented with symptoms of dry mouth and dry eye lasting more than 3 months. The patient had recovered from (PCR-confirmed) COVID-19 which lasted 10 days, 4 months ago. The physical examination was normal. Ocular findings include conjunctival hyperemia and superficial punctate keratitis. The anti-nuclear antibody (ANA) was weekly positive at 1/80. Schirmer test considered positive. He continued on 200 mg/day of hydroxychloroquine, along with tear drops until now with remission. Sicca symptoms may be a sequel of COVID-19 infection, and physicians should be aware of this sequel. The sequela of this infection is not understood, with limited data in the literature. Future prospective cohort studies are needed to reveal the impact of these features on oral health.
摘要:
几份关于2019年冠状病毒病(COVID-19)疑似口腔和眼部表现的报告促使人们对眼部体征进行调查,症状,和传播(5)。11.2%的COV19感染患者有眼部症状,包括眼痛,结膜炎,干眼症,和漂浮物,同时,许多研究记录了这些患者的口腔症状,如口干和味觉障碍。我们的病例报道了一个39岁的男性,持续3个月以上的口干和干眼症状。该患者已从(经PCR确认的)COVID-19中恢复过来,持续了10天,4个月前.体检正常。眼部表现包括结膜充血和浅表点状角膜炎。抗核抗体(ANA)在1/80时每周呈阳性。Schirmer试验为阳性。他继续服用200毫克/天的羟氯喹,随着泪滴直到现在缓解。干燥症状可能是COVID-19感染的后遗症,医生应该知道这个续集。这种感染的后遗症还不清楚,文献中的数据有限。未来的前瞻性队列研究需要揭示这些特征对口腔健康的影响。
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