Abstract：
Fatty acid synthase (FASN) is a critical enzyme essential for the production of fats in the body. The abnormal expression of FASN is associated with different types of malignancies, including ovarian cancer. FASN plays a crucial role in cell growth and survival as a metabolic oncogene, although the specific processes that cause its dysregulation are still unknown. FASN interacts with signaling pathways linked to the progression of cancer. Pharmacologically inhibiting or inactivating the FASN gene has shown potential in causing the death of cancer cells, offering a possible treatment approach. This review examines the function of FASN in ovarian cancer, namely its level of expression, influence on the advancement of the disease, and its potential as a target for therapeutic interventions.
摘要：
脂肪酸合酶（FASN）是体内脂肪产生所必需的关键酶。FASN的异常表达与不同类型的恶性肿瘤有关。包括卵巢癌.FASN作为一种代谢癌基因，在细胞生长和存活中起着至关重要的作用。尽管导致其失调的具体过程仍然未知。FASN与与癌症进展相关的信号通路相互作用。药物抑制或失活FASN基因已显示出导致癌细胞死亡的潜力，提供可能的治疗方法。本文综述了FASN在卵巢癌中的作用。即它的表达水平，对疾病进展的影响，及其作为治疗干预目标的潜力。
