Mesh : Parkinson Disease / physiopathology Humans Bayes Theorem Speech Acoustics Speech Production Measurement / methods

来  源:   DOI:10.1044/2024_JSLHR-23-00588

Abstract:
UNASSIGNED: Linguistic prosody is affected in Parkinson\'s disease (PD), which implicates the basal ganglia\'s role in the production of prosody. However, there is no recent systematic synthesis of the available acoustic evidence of prosodic impairment in PD. This study aimed to identify the acoustic features of linguistic prosody that are consistently affected in PD.
UNASSIGNED: The authors systematically reviewed articles that reported acoustic features of prosodic production in PD. Articles focused on fundamental frequency (F0) and its variability, intensity and its variability, speech and articulation rate, and pause duration and ratio. From a total of 648 records identified, 36 met criteria for inclusion and exclusion. For each acoustic measurement and task, data from people with PD (PwPD) were compared with those from controls to extract effect sizes. Pooled effect sizes were estimated using robust Bayesian hierarchical regression models.
UNASSIGNED: PD was associated with decreased F0 variability and increased pause duration. There was limited evidence of reduced intensity variability and speech rate in PwPD. No evidence was found to suggest that PD affects articulation rate or pause ratio.
UNASSIGNED: The primary acoustic parameters of prosody affected by PD are F0 variability and pause duration. The identification of these acoustic parameters has important clinical implications for the selection of PD management strategies. The association of F0 variability and pause duration with PD suggests that the neural circuits controlling these parameters are at least partly shared and might include the basal ganglia. While the current study focused on the phonetic realization of prosodic cues, future studies should examine whether and how PD affects prosody at higher levels of processing.
UNASSIGNED: https://doi.org/10.23641/asha.25892923.
摘要:
语言韵律在帕金森病(PD)中受影响,这暗示了基底神经节在韵律产生中的作用。然而,最近没有关于PD韵律损害的可用声学证据的系统综合。这项研究旨在确定在PD中始终受到影响的语言韵律的声学特征。
作者系统地回顾了报道PD中韵律产生的声学特征的文章。文章关注基频(F0)及其变异性,强度及其变异性,语音和发音率,和暂停持续时间和比率。在总共648条记录中,36符合纳入和排除标准。对于每个声学测量和任务,将PD患者(PwPD)的数据与对照组的数据进行比较,以提取效应大小.使用稳健的贝叶斯分层回归模型估计集合效应大小。
PD与F0变异性降低和暂停持续时间增加相关。PwPD中强度变异性和语速降低的证据有限。没有证据表明PD会影响发音率或停顿率。
受PD影响的韵律的主要声学参数是F0变异性和停顿持续时间。这些声学参数的识别对于PD管理策略的选择具有重要的临床意义。F0变异性和停顿持续时间与PD的关联表明,控制这些参数的神经回路至少部分共享,并且可能包括基底神经节。虽然当前的研究集中在韵律线索的语音实现上,未来的研究应该检查PD是否以及如何在更高的加工水平下影响韵律。
https://doi.org/10.23641/asha.25892923。
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