关键词: Solitary neurofibroma extraocular muscle immunohistochemistry neurofibromatosis type 1 peripheral nerve sheath tumors

来  源:   DOI:10.1080/01676830.2024.2377248

Abstract:
The present study reports a case of solitary neurofibroma attached to the Inferior Rectus (IR) muscle tendon in a 24-year-old healthy woman and reviews the relevant literature regarding the clinical presentation, diagnosis, and management of this uncommon tumor. The patient underwent successful surgical resection of the tumor, leading to the resolution of associated symptoms (left lower eyelid protrusion and redness). Pathological examination confirmed the diagnosis of neurofibroma based on characteristic histopathological and immunohistochemical markers. This case report underscores the rarity of solitary neurofibromas and primary neoplasms of orbit and ocular adnexa. We also discuss the background of solitary neurofibromas originating from orbit and ocular adnexa. The successful management of this case through surgical resection highlights the importance of accurate diagnosis and tailored treatment strategies. To the best of our knowledge, this is the first reported solitary neurofibroma confined solely to the IR tendon.
摘要:
本研究报告了一名24岁健康女性中附于下直肌(IR)肌腱的孤立性神经纤维瘤,并回顾了有关临床表现的相关文献。诊断,以及这种罕见肿瘤的治疗。患者接受了成功的肿瘤手术切除,导致相关症状(左下眼睑突出和发红)的解决。病理检查根据特征性组织病理学和免疫组织化学标记证实了神经纤维瘤的诊断。该病例报告强调了孤立性神经纤维瘤以及眼眶和眼附件的原发性肿瘤的罕见性。我们还讨论了源自眼眶和眼附件的孤立性神经纤维瘤的背景。通过手术切除成功处理此病例凸显了准确诊断和量身定制治疗策略的重要性。据我们所知,这是首次报道的仅局限于IR肌腱的孤立性神经纤维瘤.
公众号