Abstract：
BACKGROUND: Controlling the spread of arboviral diseases remains a considerable challenge due to the rapid development of insecticide resistance in Aedes mosquitoes. This study evaluated the effects of boric acid-containing toxic sugar bait (TSB) on field populations of resistant Aedes aegypti mosquitoes. In addition, this study examined the flight activity and wing beat frequency and amplitude of males and the flight activity, fecundity, and insemination of females after pairing with males exposed to TSB. The population dynamics of Aedes mosquitoes under imbalanced sex ratios were examined to simulate realistic field conditions for male suppression under the effect of TSB.
RESULTS: The mortality of male mosquitoes was consistently high within 24 h after exposure. By contrast, the mortality of female mosquitoes was inconsistent, with over 70% mortality observed at 168 h. The flight activity and wing beat amplitude of treated males were significantly lower than those of controls, but no significant difference in wing beat frequency was detected. The fecundity and insemination of treated female mosquitoes were lower than those of controls. A simulation study indicated that considerably low male population densities led to mating failures, triggering a mate-finding Allee effect and resulting in persistently low population levels.
CONCLUSIONS: Boric acid-containing TSB could effectively complement current chemical intervention approaches to control resistant mosquito populations. TSB is effective in reducing field male populations and impairing male flight activity and female-seeking behavior, resulting in decreased fecundity and insemination. Male suppression due to TSB potentially results in a small mosquito population. © 2024 Society of Chemical Industry.
RESULTS: The mortality of male mosquitoes was consistently high within 24 h after exposure. By contrast, the mortality of female mosquitoes was inconsistent, with over 70% mortality observed at 168 h. The flight activity and wing beat amplitude of treated males were significantly lower than those of controls, but no significant difference in wing beat frequency was detected. The fecundity and insemination of treated female mosquitoes were lower than those of controls. A simulation study indicated that considerably low male population densities led to mating failures, triggering a mate-finding Allee effect and resulting in persistently low population levels.
CONCLUSIONS: Boric acid-containing TSB could effectively complement current chemical intervention approaches to control resistant mosquito populations. TSB is effective in reducing field male populations and impairing male flight activity and female-seeking behavior, resulting in decreased fecundity and insemination. Male suppression due to TSB potentially results in a small mosquito population. © 2024 Society of Chemical Industry.
摘要：
背景：由于伊蚊中杀虫剂抗性的迅速发展，控制虫媒病毒病的传播仍然是一个相当大的挑战。这项研究评估了含硼酸的有毒糖饵（TSB）对抗性埃及伊蚊的田间种群的影响。此外,这项研究检查了男性的飞行活动和机翼拍频和振幅以及飞行活动，繁殖力，与暴露于TSB的雄性配对后的雌性授精。研究了性别比例不平衡下伊蚊的种群动态，以模拟TSB作用下雄性抑制的现实野外条件。
结果：雄性蚊子在暴露后24小时内的死亡率一直很高。相比之下,雌性蚊子的死亡率不一致，在168小时观察到超过70％的死亡率。接受治疗的男性的飞行活动和机翼搏动幅度显着低于对照组，但是没有检测到机翼拍频的显著差异。经治疗的雌性蚊子的繁殖力和授精率低于对照组。一项模拟研究表明，相当低的男性人口密度导致交配失败，触发了寻找伴侣的Allee效应，并导致人口水平持续低下。
结论：含硼酸的TSB可以有效地补充当前控制抗药性蚊子种群的化学干预方法。TSB可有效减少野外男性人口，损害男性飞行活动和女性寻求行为，导致繁殖力和授精减少。由于TSB引起的雄性抑制可能导致蚊子种群少。©2024化学工业学会。
结果：雄性蚊子在暴露后24小时内的死亡率一直很高。相比之下,雌性蚊子的死亡率不一致，在168小时观察到超过70％的死亡率。接受治疗的男性的飞行活动和机翼搏动幅度显着低于对照组，但是没有检测到机翼拍频的显著差异。经治疗的雌性蚊子的繁殖力和授精率低于对照组。一项模拟研究表明，相当低的男性人口密度导致交配失败，触发了寻找伴侣的Allee效应，并导致人口水平持续低下。
结论：含硼酸的TSB可以有效地补充当前控制抗药性蚊子种群的化学干预方法。TSB可有效减少野外男性人口，损害男性飞行活动和女性寻求行为，导致繁殖力和授精减少。由于TSB引起的雄性抑制可能导致蚊子种群少。©2024化学工业学会。
