PDF(Pubmed)
Abstract：
UNASSIGNED: Secretory carcinoma, previously known as mammary analog secretory carcinoma, is a rare malignancy of salivary glands. It has a diversity of microscopic patterns and is similar to other salivary gland tumors.
UNASSIGNED: This report presents the case of a 32-year-old female patient with a painless swelling of the upper lip and a history of recent surgery for an immature ovarian teratoma. The microscopic sections revealed a circumscribed neoplasm composed of macrocystic, papillary-cystic, and microcystic patterns with bland vesicular nuclei and vacuolated cytoplasm. Tumoral cells were strongly positive for mammaglobin, SOX10, GATA3, S-100, and vimentin. The diagnosis of salivary gland secretory carcinoma was made. After 22 months, there has been no recurrence.
UNASSIGNED: As secretory carcinoma is a relatively new entity, it is necessary to understand its characteristics. Although the overall incidence of second primary cancer in patients with salivary gland cancers is low, the possibility of its presence in such patients should be considered.
UNASSIGNED: This report presents the case of a 32-year-old female patient with a painless swelling of the upper lip and a history of recent surgery for an immature ovarian teratoma. The microscopic sections revealed a circumscribed neoplasm composed of macrocystic, papillary-cystic, and microcystic patterns with bland vesicular nuclei and vacuolated cytoplasm. Tumoral cells were strongly positive for mammaglobin, SOX10, GATA3, S-100, and vimentin. The diagnosis of salivary gland secretory carcinoma was made. After 22 months, there has been no recurrence.
UNASSIGNED: As secretory carcinoma is a relatively new entity, it is necessary to understand its characteristics. Although the overall incidence of second primary cancer in patients with salivary gland cancers is low, the possibility of its presence in such patients should be considered.
摘要：
■分泌性癌，以前被称为乳腺类似分泌癌，是一种罕见的唾液腺恶性肿瘤.它具有多种微观模式，与其他唾液腺肿瘤相似。
■本报告介绍了一例32岁女性患者，其上唇无痛肿胀，近期有未成熟卵巢畸胎瘤手术史。显微镜切片显示一个由大囊性肿瘤组成的局限性肿瘤，乳头状囊性，和微囊型，具有平淡的泡状核和空泡状的细胞质。肿瘤细胞对乳腺珠蛋白呈强烈阳性，SOX10、GATA3、S-100和波形蛋白。诊断为涎腺分泌癌。22个月后,没有复发。
■由于分泌性癌是一种相对较新的实体，有必要了解它的特点。尽管唾液腺癌患者第二原发癌的总体发病率较低，应考虑其在此类患者中存在的可能性。
■本报告介绍了一例32岁女性患者，其上唇无痛肿胀，近期有未成熟卵巢畸胎瘤手术史。显微镜切片显示一个由大囊性肿瘤组成的局限性肿瘤，乳头状囊性，和微囊型，具有平淡的泡状核和空泡状的细胞质。肿瘤细胞对乳腺珠蛋白呈强烈阳性，SOX10、GATA3、S-100和波形蛋白。诊断为涎腺分泌癌。22个月后,没有复发。
■由于分泌性癌是一种相对较新的实体，有必要了解它的特点。尽管唾液腺癌患者第二原发癌的总体发病率较低，应考虑其在此类患者中存在的可能性。
