PDF(Pubmed)
Abstract：
UNASSIGNED: Granular cell tumors (GCTs) are uncommon, low-grade Schwann cell tumors found in the skin, soft tissue, and mucosal surfaces of the oral, gastrointestinal, and respiratory tracts. One in 1,000 breast cancer cases is GCT. Just 1-2% of GCTs are malignant GCTs.
UNASSIGNED: This case report presents the clinical details and outcomes of a 34-year-old woman with a main concern of a palpable mass and pain in her right breast. In the clinical examination, we found a 1.5 × 2-cm palpable mass in her right breast with no axillary lymph node detection. The primary diagnosis was a benign GCT mimicking carcinoma of the breast. Upon evaluation, the mass was confirmed to be a benign GCT through pathology. The patient underwent breast-conserving surgery and sentinel lymph node dissection at the Cancer Research Center of Shahid Beheshti University of Medical Sciences on November 30, 2022. The surgical margins were found to be free of tumors, and there was no involvement of skin or axillary lymph nodes. The patient had a positive postoperative outcome, with no complications observed.
UNASSIGNED: The case highlights the importance of accurate diagnosis and appropriate surgical planning to avoid invasive procedures and unnecessary radical surgeries in cases of benign GCT mimicking carcinoma of the breast.
UNASSIGNED: This case report presents the clinical details and outcomes of a 34-year-old woman with a main concern of a palpable mass and pain in her right breast. In the clinical examination, we found a 1.5 × 2-cm palpable mass in her right breast with no axillary lymph node detection. The primary diagnosis was a benign GCT mimicking carcinoma of the breast. Upon evaluation, the mass was confirmed to be a benign GCT through pathology. The patient underwent breast-conserving surgery and sentinel lymph node dissection at the Cancer Research Center of Shahid Beheshti University of Medical Sciences on November 30, 2022. The surgical margins were found to be free of tumors, and there was no involvement of skin or axillary lymph nodes. The patient had a positive postoperative outcome, with no complications observed.
UNASSIGNED: The case highlights the importance of accurate diagnosis and appropriate surgical planning to avoid invasive procedures and unnecessary radical surgeries in cases of benign GCT mimicking carcinoma of the breast.
摘要：
■颗粒细胞瘤（GCT）并不常见，在皮肤中发现的低级施万细胞肿瘤，软组织,和口腔的粘膜表面，胃肠,和呼吸道。每1000例乳腺癌中就有一例是GCT。只有1-2%的GCT是恶性GCT。
本病例报告介绍了一名34岁女性的临床细节和结果，主要关注的是她的右乳房有明显的肿块和疼痛。在临床检查中，我们在她的右乳中发现了一个1.5×2厘米的肿块，未发现腋窝淋巴结。主要诊断是模仿乳腺癌的良性GCT。经评估，通过病理证实肿块为良性GCT。2022年11月30日，患者在ShahidBeheshti医科大学癌症研究中心接受了保乳手术和前哨淋巴结清扫术。发现手术边缘没有肿瘤，并且没有皮肤或腋窝淋巴结受累。患者术后转归为阳性,没有观察到并发症。
■该病例强调了准确诊断和适当手术计划的重要性，以避免在模仿乳腺癌的良性GCT病例中进行侵入性手术和不必要的根治性手术。
本病例报告介绍了一名34岁女性的临床细节和结果，主要关注的是她的右乳房有明显的肿块和疼痛。在临床检查中，我们在她的右乳中发现了一个1.5×2厘米的肿块，未发现腋窝淋巴结。主要诊断是模仿乳腺癌的良性GCT。经评估，通过病理证实肿块为良性GCT。2022年11月30日，患者在ShahidBeheshti医科大学癌症研究中心接受了保乳手术和前哨淋巴结清扫术。发现手术边缘没有肿瘤，并且没有皮肤或腋窝淋巴结受累。患者术后转归为阳性,没有观察到并发症。
■该病例强调了准确诊断和适当手术计划的重要性，以避免在模仿乳腺癌的良性GCT病例中进行侵入性手术和不必要的根治性手术。
