关键词: Ascorbic acid Hemorrhagic diathesis Histology Nutrition Vitamin C deficiency

来  源:   DOI:10.1159/000538916   PDF(Pubmed)

Abstract:
UNASSIGNED: Scurvy has become a rare disease in western countries with potentially high morbidity. Early diagnosis is crucial and can be challenging.
UNASSIGNED: We present the case of a 56-year-old male patient who developed hemorrhagic diathesis after trivial impact trauma. Previously, the patient suffered from fatigue and loss of appetite. Characteristic skin eruptions and a distinct skin histology along with a decreased serum vitamin C level led to the diagnosis of scurvy. Following vitamin C supplementation, symptoms improved rapidly.
UNASSIGNED: In conclusion, vitamin C deficiency should be considered in cases with unclear hemorrhagic diathesis and a medical history of nutritional irregularities. Especially in cases of scurvy that do not yet show the full clinical spectrum of symptoms or have only moderately decreased serum vitamin C levels, thorough clinical dermatological examination and a skin biopsy are essential for early diagnosis and to prevent complications.
摘要:
在西方国家,镰刀已成为一种罕见的疾病,具有潜在的高发病率。早期诊断至关重要,并且可能具有挑战性。
我们介绍了一名56岁男性患者的病例,该患者在轻微撞击创伤后出现了出血性素质。以前,患者疲劳和食欲不振。特征性的皮肤爆发和独特的皮肤组织学以及血清维生素C水平的降低导致了镰刀病的诊断。补充维生素C后,症状迅速改善。
总而言之,在出血性素质不明确且有营养异常病史的情况下,应考虑维生素C缺乏症。特别是在还没有表现出完整的临床症状谱或只有适度降低的血清维生素C水平的情况下,全面的临床皮肤病学检查和皮肤活检对于早期诊断和预防并发症至关重要。
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