PDF(Pubmed)
Abstract：
UNASSIGNED: Pilomatrix carcinomas (PMXCs) are uncommon, locally aggressive tumors with high recurrence rates, metastatic potential, and fewer than 130 cases reported in the literature. Typically, they present as an unassuming, firm, dermal swelling and therefore are frequently mistaken for more common, benign masses, leading to undertreatment which can cause local invasion and metastatic spread. Diagnosis relies on excision with pathologic analysis; however once diagnosed, there are no current recommendations to guide treatment or surveillance for recurrence or metastases.
UNASSIGNED: Here, we present a case of one of these rare tumors. Our case describes a 1.5 × 2.5 cm firm, mobile mass at the supraorbital rim in an otherwise healthy, young patient. Prior to removal, we suspected a benign pathology; however, excision proved difficult and pathologic diagnosis was consistent with PMXC. Following discussion with tumor board, decision was made to perform Mohs micrographic surgery and staging via CT scans with regular follow-up and surveillance scans.
UNASSIGNED: PMXCs are exceedingly rare diagnoses and present like many benign lesions. Therefore, we elected to document this case to encourage providers to keep these biologically aggressive tumors on their list of differential diagnoses in an unsuspecting mass, as well as to provide our own recommendations for treatment and screening for recurrence and metastatic spread.
UNASSIGNED: Here, we present a case of one of these rare tumors. Our case describes a 1.5 × 2.5 cm firm, mobile mass at the supraorbital rim in an otherwise healthy, young patient. Prior to removal, we suspected a benign pathology; however, excision proved difficult and pathologic diagnosis was consistent with PMXC. Following discussion with tumor board, decision was made to perform Mohs micrographic surgery and staging via CT scans with regular follow-up and surveillance scans.
UNASSIGNED: PMXCs are exceedingly rare diagnoses and present like many benign lesions. Therefore, we elected to document this case to encourage providers to keep these biologically aggressive tumors on their list of differential diagnoses in an unsuspecting mass, as well as to provide our own recommendations for treatment and screening for recurrence and metastatic spread.
摘要：
■Pilomatrix癌（PMXCs）并不常见，高复发率的局部侵袭性肿瘤，转移潜能,文献报道的病例不到130例。通常,他们表现得谦逊，公司，皮肤肿胀，因此经常被误认为更常见，良性肿块,导致治疗不足，可引起局部侵袭和转移扩散。诊断依赖于切除和病理分析;然而，一旦诊断，目前尚无建议指导复发或转移的治疗或监测.
■这里，我们介绍了其中一种罕见肿瘤。我们的案例描述了一个1.5×2.5厘米的公司，在其他健康的情况下，眶上边缘的移动质量，年轻的病人在移除之前，我们怀疑是良性病理；然而，切除证明困难，病理诊断与PMXC一致。在与肿瘤委员会讨论之后，我们决定进行Mohs显微手术,并通过CT扫描进行分期,同时进行定期随访和监测扫描.
■PMXCs是非常罕见的诊断，像许多良性病变一样存在。因此,我们选择记录这个案例，以鼓励提供者将这些生物学侵袭性肿瘤保留在他们的鉴别诊断列表中，以及为复发和转移扩散的治疗和筛查提供我们自己的建议。
■这里，我们介绍了其中一种罕见肿瘤。我们的案例描述了一个1.5×2.5厘米的公司，在其他健康的情况下，眶上边缘的移动质量，年轻的病人在移除之前，我们怀疑是良性病理；然而，切除证明困难，病理诊断与PMXC一致。在与肿瘤委员会讨论之后，我们决定进行Mohs显微手术,并通过CT扫描进行分期,同时进行定期随访和监测扫描.
■PMXCs是非常罕见的诊断，像许多良性病变一样存在。因此,我们选择记录这个案例，以鼓励提供者将这些生物学侵袭性肿瘤保留在他们的鉴别诊断列表中，以及为复发和转移扩散的治疗和筛查提供我们自己的建议。
