PDF(Pubmed)
Abstract：
This study aimed to evaluate the impacts of supplemental dietary curcumin on post-partum uterine involution using pulsed-wave Doppler ultrasonography in postpartum goats. Ten pluriparous Zaraibi goats were used and divided into two groups. Group 1 (n = 5; control) received only a base diet. Group 2 (n = 5; treated) received a base diet supplemented with curcumin (200 mg/kg diet) daily for 28 days, starting from day 1 postpartum (PP) till day 28 PP. Uterine morphometrical changes (uterine horn diameter; UHD and caruncle diameter; CD), uterine hemodynamics (resistance and pulsatility indices (RI and PI), systolic/ diastolic ratio (S/D), peak systolic velocity (PSV), end-diastolic velocity (EDV), blood flow volume (BFV), and blood flow rate (BFR)), and progesterone level were evaluated. Results revealed that the diameter of the uterine horn decreased rapidly from day 1 to day 10 PP (> 50%) but more steadily from day 14 to day 28 PP in both groups. After day 21 PP, there was nearly no reduction in UHD and CD in both groups. The treated group had lower values of the RI and PI (P < 0.05) than the control group. Regarding the BFR and BFV in the treated group, there was a significant increase (P < 0.05) on day 17 PP, then started to decrease till day 28 PP. While in the control group, there was a significant decrease (P < 0.05) in BFR and BFV from day 1 PP till day 28 PP. In conclusion, the incorporation of curcumin in the diet of PP Zaraibi goats improved reproductive performance via improvements in uterine morphometric changes as well as blood perfusion.
摘要：
本研究旨在使用脉冲波多普勒超声评估补充膳食姜黄素对产后山羊产后子宫复旧的影响。使用了十只多胎Zaraibi山羊，并分为两组。第1组(n=5;对照)仅接受基础饮食。第2组（n=5；治疗）每天接受补充姜黄素的基础饮食（200mg/kg饮食），持续28天，从产后第1天（PP）开始至第28天PP。子宫形态计量学变化（子宫角直径；UHD和肉梗直径；CD），子宫血流动力学(阻力和搏动指数(RI和PI)，收缩压/舒张压比（S/D），收缩期峰值速度(PSV),舒张末期血流速度(EDV),血流量（BFV），和血流量（BFR）），和孕酮水平进行评估。结果表明，两组的子宫角直径从第1天到第10天PP迅速下降（>50％），但从第14天到第28天PP更稳定。第21天PP后，两组的UHD和CD几乎没有减少.治疗组的RI和PI值低于对照组（P<0.05）。关于治疗组的BFR和BFV，第17天PP显著增加（P<0.05），然后开始下降，直到第28天。而在对照组中，从第1天PP到第28天PP，BFR和BFV显着降低（P<0.05）。总之,PPZaraibi山羊日粮中掺入姜黄素通过改善子宫形态变化和血液灌注改善了繁殖性能。
