Abstract:
Neurosarcoidosis can manifest in various neurological presentations. The occurrence of cavernous sinus involvement in neurosarcoidosis is rare, which can complicate the diagnostic process. We present a case of neurosarcoidosis demonstrating progressively deteriorating right cavernous sinus syndrome in a woman in her 50s, affecting the oculomotor, abducens and the ophthalmic division of the trigeminal nerves. MRI demonstrated meningeal thickening along the lateral wall of the right cavernous sinus, and a pan-CT scan of the chest, abdomen and pelvis revealed disseminated sarcoidosis involving the lungs and the liver. Histopathological analysis of the liver lesion ultimately confirmed the diagnosis of sarcoidosis. This case underscores the significance of considering neurosarcoidosis as a potential cause of cavernous sinus syndrome. In such cases, early initiation of corticosteroid treatment, with or without steroid-sparing agents, is crucial to prevent disease progression and relapse.
摘要:
神经结节病可以表现为各种神经系统表现。神经结节病中海绵窦受累的情况很少见,这会使诊断过程复杂化。我们介绍了一个神经结节病的病例,表明一名50多岁的女性右海绵窦综合征逐渐恶化,影响眼球运动,外展和三叉神经的眼科分裂。MRI显示右侧海绵窦外侧壁的脑膜增厚,和胸部的泛CT扫描,腹部和骨盆显示播散性结节病累及肺和肝脏。肝脏病变的组织病理学分析最终证实了结节病的诊断。此病例强调了将神经结节病视为海绵窦综合征的潜在原因的重要性。在这种情况下,早期开始皮质类固醇治疗,有或没有类固醇保护剂,对预防疾病进展和复发至关重要。