Mesh : Hydrazines / chemistry Humans HeLa Cells Imidazoles / chemistry chemical synthesis Fluorescent Dyes / chemistry chemical synthesis Optical Imaging Molecular Structure

来  源:   DOI:10.1039/d4ob01009d

Abstract:
A new chemodosimeter SWJT-31 with an aggregation-induced emission (AIE) effect was designed and constructed. Upon increasing the water fraction in the solution, it exhibited typical AIE, which showed bright red fluorescence at 610 nm. SWJT-31 could sensitively and specifically recognize hydrazine by the TICT effect with an LOD of 33.8 nM, which was much lower than the standard of the USEPA. A portable test strip prepared using SWJT-31 was also developed for the visual detection of hydrazine. Eventually, it was successfully used for the detection of hydrazine in water samples and HeLa cells.
摘要:
设计并构建了具有聚集诱导发射(AIE)效应的新型化学剂量计SWJT-31。当溶液中的水含量增加时,它展示了典型的AIE,在610nm处显示出明亮的红色荧光。SWJT-31可以通过TICT效应敏感和特异性地识别肼,LOD为33.8nM,远低于USEPA的标准。还开发了使用SWJT-31制备的便携式测试条,用于目视检测肼。最终,成功用于水样和HeLa细胞中肼的检测。
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