PDF(Pubmed)
Abstract：
Pachydermoperiostosis, also known as Touraine-Solente-Golé syndrome, is an uncommon hereditary condition. This condition includes skin thickening (pachydermia), abnormalities of the bones (periostosis), and digital clubbing (acropachy). We present a case of complete pachydermoperiostosis who presented with end-stage kidney disease. Chronic tubulointerstitial disease secondary to long-term analgesics and complementary and alternative medications was considered the likely etiology for renal dysfunction. The patient underwent serial hemodialysis followed by arteriovenous fistula surgery. In view of significant synovial inflammation, he was also given a selective COX-2 inhibitor. Pachydermoperiostosis is a rare condition, and although there is no therapy for the condition itself, medicinal or surgical interventions can effectively control its secondary effects.
摘要：
厚皮骨膜增生,也被称为Touraine-Solente-Golé综合征，是一种罕见的遗传性疾病.这种情况包括皮肤增厚（厚皮症），骨骼异常（骨膜增生），和数字俱乐部（acropachy）。我们介绍了一例患有终末期肾脏疾病的完全厚皮骨膜病。长期镇痛药和补充和替代药物继发的慢性肾小管间质疾病被认为是肾功能不全的可能病因。患者接受了连续血液透析，然后进行动静脉内瘘手术。鉴于严重的滑膜炎，他还接受了选择性COX-2抑制剂.厚皮骨膜增生是一种罕见的疾病，虽然这种情况本身没有治疗方法，药物或手术干预可以有效控制其副作用。
