PDF(Pubmed)
Abstract：
The human oral cavity is normally colonized by microorganisms including bacteria, fungi, archaea, viruses and protozoa. The aim of this study was to determine the frequency of Candida spp., in de oral cavity in a group of medical students from the north of Mexico. Oral sample were obtained from 240 healthy students. The specimens were analyzed by traditional microbiology cultures and DNA sequencing. Candida spp., grew in Sabouraud dextrose agar from 57 samples and subsequently were isolated and phenotyped. The definitive identification to the species level was done by sequence analysis. The yeasts were identified as follow: 28 Clavispora lusitaniae, 20 Candida albicans, 5 Pichia kudriavzevii and 4 Candida parapsilosis. Our findings revealed that 23.75% of the healthy population has a potential pathogen in their mouth. Surprisingly, C. albicans is not the predominant yeast; instead other non-Candida species are the colonizers of the oral cavity as normal microbiota. C. lusitaniae is considered an emerging opportunistic pathogen in immunosuppressive patients. This paper pretends to highlight the presence of this yeast in the oral cavity in immunocompetent young adults.
UNASSIGNED: The online version contains supplementary material available at 10.1007/s12088-023-01145-x.
UNASSIGNED: The online version contains supplementary material available at 10.1007/s12088-023-01145-x.
摘要：
人类口腔通常由包括细菌在内的微生物定植。真菌,古细菌,病毒和原生动物。这项研究的目的是确定念珠菌的频率。,一群来自墨西哥北部的医学生在口腔中。从240名健康学生中获取口腔样本。通过传统微生物学培养和DNA测序对标本进行分析。念珠菌属。,从57个样品中在Sabouraud葡萄糖琼脂中生长，随后进行分离和表型分析。通过序列分析对物种水平进行了明确的鉴定。酵母的鉴定如下：28个Clavisporalusitaniae，20白色念珠菌,5个毕赤酵母和4个近带念珠菌。我们的发现显示，23.75％的健康人群在其口腔中具有潜在的病原体。令人惊讶的是,白色念珠菌不是主要的酵母;相反,其他非念珠菌属物种是口腔正常微生物群的定植者。在免疫抑制患者中,柳树杆菌被认为是新兴的机会性病原体。本文假装强调这种酵母在具有免疫能力的年轻人的口腔中的存在。
■在线版本包含补充材料，可在10.1007/s12088-023-01145-x获得。
■在线版本包含补充材料，可在10.1007/s12088-023-01145-x获得。
