Brain function was measured at age 3 using 5 measures which formed a reliable composite (neurological examination, cognitive and motor tests, and temperament ratings). Physical function was measured at age 45 using 5 measures which formed a reliable composite (gait speed, step-in-place, chair stands, balance, and grip strength).
Children with worse age-3 brain function had worse midlife physical function as measured by the age-45 composite, even after controlling for childhood socioeconomic status (β: 0.23; 95% CI: 0.16 to 0.30; p < .001). Worse age-3 brain function significantly predicted slower gait speed, fewer steps-in-place and chair-stands, worse balance, and weaker grip strength.
Children with poorer brain function were more likely to have poorer physical-function scores as adults. In addition to indicating recent musculoskeletal decline, physical-function tests may also provide indications of lifelong, integrated brain-body health. By reconceptualizing the meaning of physical-function scores, clinicians can orient the use of physical-function tests in a more holistic approach to health care.
方法:在3岁时使用五种方法测量脑功能,这些方法形成了可靠的综合(神经学检查,认知和运动测试,气质评级)。在45岁时使用五种测量方法测量身体功能,这些测量形成了可靠的复合材料(步态速度,步骤到位,椅子的立场,balance,握力)。
结果:以45岁复合指数衡量,3岁大脑功能较差的儿童中年身体功能较差,即使在控制了儿童社会经济地位(β,0.23;95%CI,0.16-0.30;P<.001)。更糟糕的3岁大脑功能显着预测步态速度较慢,更少的台阶和椅子支架,更差的平衡,和较弱的握力。
结论:大脑功能较差的儿童与成年人相比,身体功能评分较差的可能性更大。除了表明最近的肌肉骨骼下降,身体功能测试也可以提供终身的迹象,综合脑体健康。通过重新概念化身体功能评分的含义,临床医生可以在更全面的医疗保健方法中指导身体功能测试的使用。