UNASSIGNED: To examine the impact of polyphenol-rich foods on lipid levels and oxidative stress in individuals with hyperlipidemia.
UNASSIGNED: To retrieve papers published from the establishment of the database through October 9, 2023, eight databases were searched: the Chinese National Knowledge Infrastructure, the China Biomedical Literature Database, the Wanfang Database, the China Science and Technology Journal Database, PubMed, the Cochrane Library, Embase, and the Web of Science. The quality of include studies was assessed using the Cochrane Risk of Bias in Randomized Trials tool, v2.
UNASSIGNED: The study involved 13 surveys encompassing 640 patients diagnosed with hyperlipidemia. The scope of the food surveys included 12 commonly consumed food groups and medicinal and food homologous substances. All 13 studies reported the effects of polyphenol-rich foods on blood lipids, with significant improvements observed in blood lipid levels for 9 types of foods. Eight studies examined the impact on oxidative stress, and six foods demonstrated a significant reduction in oxidative stress levels. The observed effects were found to be influenced by factors such as dosage, duration of intervention, and gender.
UNASSIGNED: Foods abundant in polyphenols play a crucial role in the prevention and treatment of hyperlipidemia by counteracting oxidative stress and regulating metabolic disorders. The confirmation of certain positive effects by several studies notwithstanding, discrepancies in results arise from various factors, necessitating further large-scale, prospective, well-designed randomized controlled studies to address this issue.
■研究富含多酚的食物对高脂血症患者血脂水平和氧化应激的影响。
■为了检索到2023年10月9日从数据库建立中发表的论文,搜索了八个数据库:中国国家知识基础设施,中国生物医学文献数据库,万方数据库,中国科技期刊数据库,PubMed,Cochrane图书馆,Embase,和WebofScience.使用随机试验工具中的Cochrane偏差风险评估纳入研究的质量,V2.
■该研究涉及13项调查,包括640名被诊断为高脂血症的患者。食品调查的范围包括12种常用食品类别以及药用和食品同源物质。所有13项研究都报道了富含多酚的食物对血脂的影响,9种食物的血脂水平显着改善。八项研究检查了对氧化应激的影响,六种食物的氧化应激水平显着降低。发现观察到的效果受剂量,干预的持续时间,和性别。
■富含多酚的食物通过抵抗氧化应激和调节代谢紊乱在预防和治疗高脂血症中起着至关重要的作用。尽管有几项研究证实了某些积极作用,结果的差异是由各种因素引起的,需要进一步大规模,prospective,精心设计的随机对照研究来解决这个问题。