关键词: Bladder cancer Cone-beam computed tomography Image-guided radiotherapy Linear accelerator Online adaptive radiotherapy (oART)

来  源:   DOI:10.1016/j.phro.2024.100597   PDF(Pubmed)

Abstract:
Current online adaptive radiotherapy (oART) workflows require dedicated equipment. Our aim was to develop and implement an oART workflow for a C-arm linac which can be performed using standard clinically available tools. A workflow was successfully developed and implemented. Three patients receiving palliative radiotherapy for bladder cancer were treated, with 33 of 35 total fractions being delivered with the cone-beam computed tomography (CBCT)-guided oART workflow. Average oART fraction duration was 24 min from start of CBCT acquisition to end of beam on. This work shows how oART could be performed without dedicated equipment, broadening oART availability for application at existing treatment machines.
摘要:
当前的在线自适应放射治疗(oART)工作流程需要专用设备。我们的目标是为C臂直线加速器开发和实施oART工作流程,该工作流程可以使用标准的临床可用工具进行。成功开发并实施了工作流。对3例接受膀胱癌姑息性放疗的患者进行了治疗,35个总部分中的33个通过锥形束计算机断层扫描(CBCT)引导的oART工作流程交付。从CBCT采集开始到光束结束的平均oART片段持续时间为24分钟。这项工作展示了如何在没有专用设备的情况下执行oART,扩大oART的可用性,适用于现有的治疗机。
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