PDF(Pubmed)
Abstract：
We present a case of a 50-year-old male who initially presented to the clinic with complaints of palpitations, shortness of breath, dizziness, night sweats, headaches with associated intermittent episodes of diarrhea, episodes of flushing, and rash on the upper body. Laboratory testing revealed elevated chromogranin A levels. Initial imaging with computed tomography (CT) of the abdomen and pelvis with contrast was negative for any lesions. However, due to his clinical presentation and high suspicion of a neuroendocrine tumor (NET), a positron emission tomography-CT (PET-CT) scan with Gallium 68-DOTATATE was obtained, confirming and localizing his NET in the neck of the pancreas and the liver. Following confirmation and localization of his tumor, he was referred for surgical evaluation and treatment. Pancreatic neuroendocrine tumors are rare and difficult to diagnose, highlighted by unsuccessful initial efforts to localize and confirm the tumor. This case underscores the importance of clinical suspicion and acumen in diagnosing neuroendocrine tumors. Upcoming imaging modalities of PET-CT scans provide promising avenues to uncover neuroendocrine tumors.
摘要：
我们介绍了一个50岁的男性，他最初出现在诊所，抱怨心悸，呼吸急促,头晕,盗汗,头痛伴有间歇性腹泻，潮红发作，上身有皮疹.实验室测试显示嗜铬粒蛋白A水平升高。腹部和骨盆的计算机断层扫描（CT）的初始成像对任何病变均为阴性。然而,由于他的临床表现和高度怀疑神经内分泌肿瘤（NET），获得了68-DOTATATE镓的正电子发射断层扫描-CT（PET-CT）扫描，在胰腺和肝脏的颈部确认并定位他的网。在他的肿瘤得到确认和定位后,他被转诊接受手术评估和治疗。胰腺神经内分泌肿瘤罕见且难以诊断，最初的定位和确认肿瘤的努力不成功。此病例强调了临床怀疑和敏锐在诊断神经内分泌肿瘤中的重要性。即将到来的PET-CT扫描成像模式为发现神经内分泌肿瘤提供了有希望的途径。
