关键词: anti-microbial dentifrice herbal homeopathy oral microflora

来  源:   DOI:10.7759/cureus.62197   PDF(Pubmed)

Abstract:
Aim To assess the antimicrobial activity of herbal, homeopathic, and conventional dentifrices against oral microorganisms. Methodology Mueller Hilton agar was used to cultivate distinct strains of Streptococcus mutans and Enterococcus faecalis, whereas Candida albicans was cultured on a potato dextrose agar medium. Diffusion ratios of 1:5, 1:10, and 1:15 were obtained by diluting 1 gram of each dentifrice (KP Namboodiri, Homeodent, and Colgate Strong Teeth) in 4 ml, 9 ml, and 14 ml of distilled water, respectively. The culture medium was filled with sterile discs. Twenty μl of each dilution of prepared dentifrice formulations were incorporated using a micropipette. The agar plates were incubated for 24 hours at 37ºC. Result The findings indicate that there was a higher zone of inhibition against Streptococcus mutans with herbal dentifrice at 10 mm, 8 mm, and 6.5 mm, followed by conventional dentifrice at 10 mm, 7.5 mm, and 7 mm, and the lowest with homeopathic dentifrice at 8 mm, 7 mm, and 7 mm at 1:5, 1:10 and 1:15 dilutions, respectively. Conventional dentifrice was found to inhibit Enterococcus faecalis at 9 mm, 8 mm, and 7 mm with 1:5, 1:10, and 1:15 dilutions followed by herbal dentifrice at 9 mm, 7 mm with 1:5, 1:10 dilutions, and no inhibition at 1:15 dilution. In contrast, homeopathic dentifrice displayed no inhibition at 1:5, 1:10, and 1:15 dilutions. Neither homeopathic nor conventional dentifrices inhibited Candida albicans, but herbal dentifrices showed a 10 mm zone of inhibition at 1:10 dilution. Conclusion Conventional and herbal dentifrices were found to be more effective against Streptococcus mutans than the homeopathic dentifrice used in the study, whereas herbal dentifrice was more effective against Candida albicans when compared to conventional and homeopathic dentifrices.
摘要:
目的评估中草药的抗菌活性,顺势疗法,和抗口腔微生物的常规洁牙剂。方法使用MuellerHilton琼脂培养变形链球菌和粪肠球菌的不同菌株,而白色念珠菌在马铃薯葡萄糖琼脂培养基上培养。通过稀释1克每种牙粉(KPNamboodiri,Homeodent,和高露洁强牙)在4毫升,9毫升,和14毫升蒸馏水,分别。用无菌圆盘填充培养基。使用微量移液管掺入20μl制备的洁齿剂制剂的每种稀释液。琼脂平板在37ºC孵育24小时。结果发现,10mm的草药牙膏对变形链球菌的抑制作用较高,8mm,和6.5毫米,其次是10毫米的传统牙膏,7.5mm,7毫米,最低的顺势疗法洁齿剂为8毫米,7毫米,以1:5、1:10和1:15稀释为7毫米,分别。发现常规洁齿剂在9毫米处抑制粪肠球菌,8mm,7毫米,1:5、1:10和1:15稀释,然后用9毫米的草药洁齿剂,7毫米,1:5,1:10稀释,并且在1:15稀释时没有抑制。相比之下,顺势疗法洁齿剂在1:5、1:10和1:15稀释度时没有显示出抑制作用。顺势疗法和常规洁牙剂都不能抑制白色念珠菌,但草药洁牙剂在1:10稀释时显示出10毫米的抑制区。结论本研究中发现常规和中草药洁牙剂对变形链球菌的治疗效果优于顺势疗法洁牙剂,而与常规和顺势疗法洁齿剂相比,草药洁齿剂对白色念珠菌更有效。
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