关键词: B-cell lymphoma MALT lacrimal gland lymphomas orbital tumors

Mesh : Humans Male Aged, 80 and over Lacrimal Apparatus Diseases / diagnosis surgery Magnetic Resonance Imaging Tomography, X-Ray Computed Eye Neoplasms / diagnosis surgery therapy Lacrimal Apparatus / pathology surgery diagnostic imaging Lymphoma, Large B-Cell, Diffuse / diagnosis surgery Lymphoma, B-Cell, Marginal Zone / diagnosis surgery Visual Acuity Ophthalmologic Surgical Procedures / methods Biopsy

来  源:   DOI:10.22336/rjo.2024.36   PDF(Pubmed)

Abstract:
Lacrimal gland lymphomas are rare orbital tumors, constituting a minor fraction of all orbital and ocular adnexal malignancies. This case study presents an 83-year-old male with bilateral lacrimal gland tumors, more prominent in the left orbit, causing decreased visual acuity, red eye, excessive tearing, and diplopia. Initial ophthalmological evaluations and imaging suggested bilateral lacrimal gland lymphoma, confirmed by histopathology as diffuse large B-cell non-Hodgkin lymphoma of the MALT type. Due to the significant tumor size and risk of visual function loss, surgical intervention was performed, followed by corticosteroid therapy. Postoperatively, a marked improvement in symptoms and a reduction in tumor size were observed. This case underscores the importance of comprehensive diagnostic approaches, including clinical, imaging, and histopathological evaluations, highlighting the need for a multidisciplinary approach in managing rare orbital tumors like lacrimal gland lymphoma. The patient\'s postoperative and follow-up care included oncological management to monitor and ensure long-term disease control and patient well-being. Abbreviations: RE = right eye, LE = left eye, CT = Computer tomography, MRI = Magnetic Resonance Imaging, TOD = intraocular pressure of right eye, TOS = intraocular pressure of left eye, US = ultrasound.
摘要:
泪腺淋巴瘤是罕见的眼眶肿瘤,构成所有眼眶和眼附件恶性肿瘤的一小部分。该病例研究介绍了一名83岁的男性,患有双侧泪腺肿瘤,在左轨道上更突出,导致视力下降,红眼,过度撕裂,和复视。最初的眼科评估和影像学检查提示双侧泪腺淋巴瘤,经组织病理学证实为MALT型弥漫性大B细胞非霍奇金淋巴瘤。由于显著的肿瘤大小和视觉功能丧失的风险,进行了手术干预,其次是皮质类固醇治疗。术后,观察到症状明显改善,肿瘤大小减小.这个案例强调了全面诊断方法的重要性,包括临床,成像,和组织病理学评估,强调需要多学科方法来治疗罕见的眼眶肿瘤,如泪腺淋巴瘤。患者的术后和随访护理包括肿瘤管理,以监测和确保长期疾病控制和患者健康。缩写:RE=右眼,LE=左眼,CT=计算机断层扫描,MRI=磁共振成像,TOD=右眼的眼压,TOS=左眼眼压,US=超声。
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