PDF(Pubmed)
Abstract：
UNASSIGNED: Lichen sclerosus is a chronic inflammatory dermatological condition of unknown etiology, primarily impacting the genital epidermis in individuals of all genders, with a higher prevalence observed among postmenopausal women and prepubescent girls. Additionally, extragenital manifestations occur in approximately 20% of the patients diagnosed with genital lichen sclerosus. Notably, folliculocentric extragenital lichen sclerosus is rare and unusual, with only limited instances documented in existing literature.
UNASSIGNED: We report a 33 years old lady presented with multiple asymptomatic lesions on the dorsal feet for 1 year and similar lesions on the left hand for 4 months. On examination: folliculocentric, shiny, atrophic papules coalescing into reticulated plaques over the dorsum of both feet and few shiny, flat-topped, pink papules over the dorsum of the left hand. A skin biopsy was performed and confirmed the diagnosis of extragenital lichen sclerosus.
UNASSIGNED: Acral folliculocentric extragenital lichen sclerosus is an unusual and rare clinical variant. Clinicopathologic correlation is necessary to establish the correct diagnosis.
UNASSIGNED: Herein, we present an unusual presentation of extragenital lichen sclerosus, and we highlight the importance of considering it in the differential diagnosis of guttate acral skin lesions. We also review and summarize relevant cases from the literature in hope to aid physicians, especially dermatologists, to consider and swiftly reach the diagnosis and offer appropriate management. We also hope to bring about new insights and broaden future research efforts regarding lichen sclerosus especially and atrophic skin disease in general.
UNASSIGNED: We report a 33 years old lady presented with multiple asymptomatic lesions on the dorsal feet for 1 year and similar lesions on the left hand for 4 months. On examination: folliculocentric, shiny, atrophic papules coalescing into reticulated plaques over the dorsum of both feet and few shiny, flat-topped, pink papules over the dorsum of the left hand. A skin biopsy was performed and confirmed the diagnosis of extragenital lichen sclerosus.
UNASSIGNED: Acral folliculocentric extragenital lichen sclerosus is an unusual and rare clinical variant. Clinicopathologic correlation is necessary to establish the correct diagnosis.
UNASSIGNED: Herein, we present an unusual presentation of extragenital lichen sclerosus, and we highlight the importance of considering it in the differential diagnosis of guttate acral skin lesions. We also review and summarize relevant cases from the literature in hope to aid physicians, especially dermatologists, to consider and swiftly reach the diagnosis and offer appropriate management. We also hope to bring about new insights and broaden future research efforts regarding lichen sclerosus especially and atrophic skin disease in general.
摘要：
■硬化性苔藓是一种病因不明的慢性炎症性皮肤病，主要影响所有性别个体的生殖器表皮，在绝经后妇女和青春期前女孩中观察到较高的患病率。此外,在诊断为生殖器硬化性苔藓的患者中，约有20％出现生殖器外表现。值得注意的是,以卵泡为中心的生殖器外硬化性苔藓是罕见且不寻常的，现有文献中仅记录了有限的实例。
■我们报告了一名33岁的女士，其背足有多个无症状的病变1年，左手有类似的病变4个月。检查：卵泡中心，闪亮，萎缩性丘疹在双脚的背部合并成网状斑块，很少有光泽，平顶,左手背部有粉红色丘疹。进行了皮肤活检，并证实了生殖器外硬化性苔藓的诊断。
■以卵泡为中心的生殖器外硬化性苔藓是一种罕见且罕见的临床变异。临床病理相关性对于建立正确的诊断是必要的。
■这里，我们提出了一种不寻常的外皮硬化苔藓，我们强调了在鉴别诊断点滴状肢部皮肤病变时考虑它的重要性。我们还从文献中回顾和总结相关案例，希望对医生有所帮助，尤其是皮肤科医生,考虑并迅速达到诊断并提供适当的管理。我们也希望带来新的见解，并扩大未来的研究工作，特别是关于硬化性苔藓和萎缩性皮肤病。
■我们报告了一名33岁的女士，其背足有多个无症状的病变1年，左手有类似的病变4个月。检查：卵泡中心，闪亮，萎缩性丘疹在双脚的背部合并成网状斑块，很少有光泽，平顶,左手背部有粉红色丘疹。进行了皮肤活检，并证实了生殖器外硬化性苔藓的诊断。
■以卵泡为中心的生殖器外硬化性苔藓是一种罕见且罕见的临床变异。临床病理相关性对于建立正确的诊断是必要的。
■这里，我们提出了一种不寻常的外皮硬化苔藓，我们强调了在鉴别诊断点滴状肢部皮肤病变时考虑它的重要性。我们还从文献中回顾和总结相关案例，希望对医生有所帮助，尤其是皮肤科医生,考虑并迅速达到诊断并提供适当的管理。我们也希望带来新的见解，并扩大未来的研究工作，特别是关于硬化性苔藓和萎缩性皮肤病。
