关键词: Schlemm’s canal anterior scleral thickness high myopia primary open-angle glaucoma trabecular meshwork

来  源:   DOI:10.3389/fmed.2024.1356839   PDF(Pubmed)

Abstract:
UNASSIGNED: This study aimed to investigate and compare the anterior scleral thickness (AST) among high myopia (HM), primary open-angle glaucoma (POAG), and POAG with HM (HMPOAG) groups.
UNASSIGNED: Thirty-two HM eyes, 30 POAG eyes, and 31 HMPOAG eyes were included. The Schlemm\'s canal (SC) area, trabecular meshwork (TM) thickness, scleral spur (SS) length, and AST were measured using swept-source optical coherence tomography. AST was measured at 0 mm (AST0), 1 mm (AST1), 2 mm (AST2), and 3 mm (AST3) from SS.
UNASSIGNED: The HMPOAG group had significantly thinner AST, SS length, and TM thickness than the HM and POAG groups (all p < 0.05). In addition, the SC area of the HMPOAG group was also significantly smaller than that of the HM group (p < 0.001).
UNASSIGNED: The HMPOAG group had the thinnest AST, shortest SS, thinnest TM, and smallest SC. The thinnest AST might contribute to the shortest SS, and further to the thinnest TM and smallest SC in the HMPOAG group. AST might be a novel clinical indicator in the prediction and evaluation of POAG.
摘要:
本研究旨在调查和比较高度近视(HM)的前巩膜厚度(AST),原发性开角型青光眼(POAG),和POAG与HM(HMPOAG)组。
32只HM眼睛,30只POAG眼睛,包括31只HMPOAG眼。施莱姆运河(SC)区,小梁网(TM)厚度,巩膜骨刺(SS)长度,和AST是使用扫频源光学相干断层扫描测量的。AST在0mm(AST0)处测量,1mm(AST1),2mm(AST2),和3毫米(AST3)从SS。
HMPOAG组的AST明显变薄,SS长度,TM厚度高于HM和POAG组(均p<0.05)。此外,HMPOAG组的SC面积也显著小于HM组(p<0.001)。
HMPOAG组的AST最薄,最短SS,最薄的TM,最小的SC最薄的AST可能有助于最短的SS,进一步到HMPOAG组中最薄的TM和最小的SC。AST可能是预测和评价POAG的新临床指标。
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