Abstract：
Autonomous sensory meridian response (ASMR) is characterized by a tingling sensation with a feeling of relaxation and a state of flow. We explore the neural underpinnings and comorbidities of ASMR and related phenomena with altered sensory processing. These phenomena include sensory processing sensitivity (SPS), synaesthesia, Alice in Wonderland syndrome and misophonia. The objective of this article is to uncover the shared neural substrates and distinctive features of ASMR and its counterparts. ASMR, SPS and misophonia exhibit common activations in the brain regions associated with social cognition, emotion regulation and empathy. Nevertheless, ASMR responders display reduced connectivity in the salience network (SN), while individuals with SPS exhibit increased connectivity in the SN. Furthermore, ASMR induces relaxation and temporarily reduces symptoms of depression, in contrast to SPS and misophonia, which are linked to depression. These observations lead us to propose that ASMR is a distinct phenomenon owing to its attention dispatch mechanism and its connection with emotion regulation. We suggest that increased activations in the insula, along with reduction in connectivity within the salience and default mode networks in ASMR responders, may account for their experiences of relaxation and flow states. This article is part of the theme issue \'Sensing and feeling: an integrative approach to sensory processing and emotional experience\'.
摘要：
自主感觉子午线反应（ASMR）的特征是刺痛感，具有放松感和流动状态。我们探索了ASMR的神经基础和合并症以及相关的感觉加工改变的现象。这些现象包括感官加工敏感性(SPS)，通感,爱丽丝梦游仙境综合症和异音。本文的目的是揭示ASMR及其对应物的共同神经基质和独特特征。ASMR,SPS和错音在与社会认知相关的大脑区域表现出共同的激活，情绪调节和移情。然而，ASMR响应者显示显著网络(SN)中的连通性降低，而患有SPS的个体在SN中表现出增加的连通性。此外，ASMR诱导放松并暂时减轻抑郁症状，与SPS和立体声声相反，这与抑郁症有关。这些观察结果使我们提出，由于其注意力调度机制及其与情绪调节的联系，ASMR是一种独特的现象。我们建议增加脑岛的激活，随着ASMR响应器的显著性和默认模式网络内连通性的减少，可以解释他们放松和流动状态的经历。本文是主题为“感觉和感觉：感觉处理和情感体验的综合方法”的一部分。
