METHODS: Ninety-five consecutive patients with HNRMS newly diagnosed at one institution between November 2011 and July 2023 were retrospectively reviewed. All the patients underwent head and neck contrast-enhanced MRI and/or CT, PET-CT if necessary. The associations between LNMs and clinical characteristics and histopathological parameters were discovered.
RESULTS: 44.2% of patients had evidence of LNM at diagnosis, and the most common LNM occurred in the ipsilateral retropharyngeal space. The primary tumor metastasizes to the retropharyngeal space, and then next to level II is the most common LN drainage basin. In multivariate analysis, only distant metastasis determines the prognosis, other than LN status.
CONCLUSIONS: LNM has a high incidence in HNRMS and rarely causes contralateral metastasis for localized lesions or skip metastasis.
方法:回顾性分析了2011年11月至2023年7月在一家机构新诊断的95例HNRMS患者。所有患者均行头颈部对比增强MRI和/或CT检查,必要时使用PET-CT。发现了LNM与临床特征和组织病理学参数之间的关联。
结果:44.2%的患者在诊断时具有LNM的证据,最常见的LNM发生在同侧咽后间隙。原发肿瘤转移到咽后间隙,然后在II级旁边是最常见的LN流域。在多变量分析中,只有远处转移决定预后,除了LN状态。
结论:LNM在HNRMS中的发病率很高,很少引起局部病变或跳跃转移的对侧转移。