PDF(Pubmed)
Abstract：
BACKGROUND: Magnetic resonance imaging (MRI) of the brain is frequently performed on patients with neurofibromatosis type 1 (NF1), to detect and follow-up intracranial findings. In addition, NF1-related pathologies can appear in the jaws. This case study investigates if it is advantageous to assess the depicted parts of the jaws in the imaging of NF1 patients with intracranial findings, thereby detecting jaw pathologies in their initial stages.
METHODS: We report on the 3-year management with clinical and radiological follow-ups of a central giant cell granuloma and a neurofibroma in the mandible of a patient with NF1 who underwent examinations with brain MRIs. A review of the mandible in the patient\'s MRIs disclosed lesions with clear differences in progression rates.
CONCLUSIONS: NF1-related jaw pathologies may be detected in the early stages if the depicted parts of the jaws are included in the assessment of the imaging of NF1 patients with intracranial findings. This could impact the treatment of eventual pathologies before lesion progression and further damage to the vicinity.
METHODS: We report on the 3-year management with clinical and radiological follow-ups of a central giant cell granuloma and a neurofibroma in the mandible of a patient with NF1 who underwent examinations with brain MRIs. A review of the mandible in the patient\'s MRIs disclosed lesions with clear differences in progression rates.
CONCLUSIONS: NF1-related jaw pathologies may be detected in the early stages if the depicted parts of the jaws are included in the assessment of the imaging of NF1 patients with intracranial findings. This could impact the treatment of eventual pathologies before lesion progression and further damage to the vicinity.
摘要：
背景：通常对1型神经纤维瘤病（NF1）患者进行脑部磁共振成像（MRI），检测和随访颅内发现。此外,NF1相关的病理可以出现在颌骨中。本案例研究调查了在NF1患者颅内发现的成像中评估颌骨的描绘部分是否有利，从而在初始阶段检测颌骨病变。
方法：我们报告了NF1患者的3年治疗以及临床和放射学随访，该患者接受了脑MRI检查，其下颌骨中的中央巨细胞肉芽肿和神经纤维瘤。对患者MRI下颌骨的回顾发现病变的进展率存在明显差异。
结论：如果在对NF1患者颅内发现的影像学评估中包括所描绘的颌骨部分，则可以在早期阶段检测到NF1相关的颌骨病变。这可能会影响在病变进展之前对最终病理的治疗以及对附近的进一步损害。
方法：我们报告了NF1患者的3年治疗以及临床和放射学随访，该患者接受了脑MRI检查，其下颌骨中的中央巨细胞肉芽肿和神经纤维瘤。对患者MRI下颌骨的回顾发现病变的进展率存在明显差异。
结论：如果在对NF1患者颅内发现的影像学评估中包括所描绘的颌骨部分，则可以在早期阶段检测到NF1相关的颌骨病变。这可能会影响在病变进展之前对最终病理的治疗以及对附近的进一步损害。
