关键词: Cerebral arteriovenous malformation Eclampsia Endovascular embolization Gestational hypertension Headache Seizure

Mesh : Humans Female Pregnancy Eclampsia / diagnosis Adult Seizures / etiology diagnosis Headache / etiology Diagnosis, Differential Intracranial Arteriovenous Malformations / complications diagnosis therapy Cesarean Section Magnetic Resonance Imaging Embolization, Therapeutic Pregnancy Complications, Cardiovascular / diagnosis therapy Tomography, X-Ray Computed Pregnancy Trimester, Third

来  源:   DOI:10.1016/j.tjog.2023.09.026

Abstract:
OBJECTIVE: Cerebral arteriovenous malformation during pregnancy is rare but lethal disease that usually present with new-onset seizures and headaches mimicking eclampsia. We report a rare case of cerebral arteriovenous malformation with abrupt seizures in the third trimester.
METHODS: A 28-year-old primipara was brought to our emergency department at 32 6/7 weeks of gestation with new-onset acute seizures and hypertension. Owing to neurological deterioration, the patient underwent emergency cesarean delivery. However, 24 h after cesarean delivery and eclampsia treatment, the seizures worsened. Computed tomography and magnetic resonance imaging showed unruptured arteriovenous malformation of the right frontal lobe. Subsequently, intraarterial embolization was performed. The patient was discharged 5 days after surgery without neurological sequelae or obstetric complications.
CONCLUSIONS: This case report highlights the differential diagnoses of sudden new-onset seizures in late pregnancy for obstetricians and emergency medicine physicians. Lethal cerebral diseases, apart from eclampsia, should be considered during pregnancy.
摘要:
目的:妊娠期脑动静脉畸形是一种罕见但致命的疾病,通常表现为模仿子痫的新发作性癫痫和头痛。我们报告了一例罕见的脑动静脉畸形,并在妊娠晚期突然发作。
方法:一名28岁的初产妇在妊娠326/7周时被带到我们的急诊科,新发急性癫痫发作和高血压。由于神经恶化,患者接受了紧急剖宫产。然而,剖宫产和子痫治疗后24h,癫痫发作恶化。计算机断层扫描和磁共振成像显示右额叶动静脉畸形未破裂。随后,进行动脉内栓塞.患者术后5天出院,无神经后遗症或产科并发症。
结论:本病例报告重点介绍了产科医生和急诊医师对妊娠晚期突然新发癫痫的鉴别诊断。致命的脑部疾病,除了子痫,应该在怀孕期间考虑。
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