Abstract:
Patients with malabsorptive conditions can develop micronutrient deficiencies, even if they receive vitamins, minerals, or trace elements through their enteral or parenteral nutrition. Additionally, clinicians have faced challenges with micronutrient supplementation during parenteral product shortages and when transitioning patients from parenteral to enteral/oral nutrition. Evaluating micronutrient deficiencies through laboratory markers has various limitations, including that many are acute phase reactants, may not reflect storage status, or may not be readily available in clinical practice. Furthermore, clinicians can become overwhelmed with the variety of vitamin and mineral products available, the differences in dosages and ingredients in these products, and lastly, the inherent challenges associated with an impaired gastrointestinal tract. The current review will discuss some challenges clinicians may encounter in clinical practice during the evaluation, assessment, and prescription of micronutrient supplementation in patients with malabsorptive conditions.
摘要:
吸收不良的患者会出现微量营养素缺乏症,即使他们接受了维生素,矿物,或微量元素通过肠内或肠外营养。此外,在肠胃外产品短缺期间以及将患者从肠胃外营养过渡到肠内/口服营养时,临床医生在补充微量营养素方面面临挑战。通过实验室标记评估微量营养素缺乏有各种局限性,包括许多是急性相反应物,可能无法反映存储状态,或者在临床实践中可能不容易获得。此外,临床医生可能会对各种可用的维生素和矿物质产品感到不知所措,这些产品中剂量和成分的差异,最后,与胃肠道受损相关的固有挑战。本综述将讨论临床医生在评估期间在临床实践中可能遇到的一些挑战,评估,以及吸收不良患者补充微量营养素的处方。