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Abstract：
BACKGROUND: Deep venous thrombosis (DVT) is a serious public health issue that threatens human health and economic development. Presently, differences in the prevalence of DVT among individuals from different nationalities, residents of high-altitude areas, and those consuming any special diet are unknown. Therefore, we aimed to elucidate the prevalence of and the associated risk factors for DVT in hospitalized patients in the plateau areas.
METHODS: The subjects were hospitalized patients in three grade III-a hospitals in the Qinghai Province, China, during January-October 2020. The demographic, clinical, and laboratory data were collected at admission, and ultrasonography of the bilateral lower extremities was performed. The hospital stay-duration was recorded at the time of discharge.
RESULTS: A total of 3432 patients were enrolled, of which 159 (4.60%) were diagnosed with DVT. The age of > 50 years (OR = 2.434, 95% CI: 1.521-3.894252, P < 0.001), residence altitude of ≥ 3000 m (OR = 2.346, 95% CI: 1.239-4.440, P = 0.009), D-dimer level of ≥ 0.5 mg/L (OR = 2.211, 95% CI: 1.547-3.161, P < 0.001), presence of comorbidities (OR = 1.904, 95% CI: 1.386-2.705, P < 0.001), a history of varicose veins (OR = 1.990, 95% CI: 0.959-4.128, P = 0.045), and current medications (OR = 2.484, 95% CI: 1.778-3.471, P < 0.001) were identified as risk factors for DVT in these plateau areas.
CONCLUSIONS: The prevalence of DVT in the hospitalized patients of the studied plateau areas was 4.60%. We recommend considering individualized risk stratification (age > 50 years, residence altitude ≥ 3000 m, a history of varicose veins, D-dimer level ≥ 0.5 mg/L, current medications, and comorbidities) for patients at the time of admission.
METHODS: The subjects were hospitalized patients in three grade III-a hospitals in the Qinghai Province, China, during January-October 2020. The demographic, clinical, and laboratory data were collected at admission, and ultrasonography of the bilateral lower extremities was performed. The hospital stay-duration was recorded at the time of discharge.
RESULTS: A total of 3432 patients were enrolled, of which 159 (4.60%) were diagnosed with DVT. The age of > 50 years (OR = 2.434, 95% CI: 1.521-3.894252, P < 0.001), residence altitude of ≥ 3000 m (OR = 2.346, 95% CI: 1.239-4.440, P = 0.009), D-dimer level of ≥ 0.5 mg/L (OR = 2.211, 95% CI: 1.547-3.161, P < 0.001), presence of comorbidities (OR = 1.904, 95% CI: 1.386-2.705, P < 0.001), a history of varicose veins (OR = 1.990, 95% CI: 0.959-4.128, P = 0.045), and current medications (OR = 2.484, 95% CI: 1.778-3.471, P < 0.001) were identified as risk factors for DVT in these plateau areas.
CONCLUSIONS: The prevalence of DVT in the hospitalized patients of the studied plateau areas was 4.60%. We recommend considering individualized risk stratification (age > 50 years, residence altitude ≥ 3000 m, a history of varicose veins, D-dimer level ≥ 0.5 mg/L, current medications, and comorbidities) for patients at the time of admission.
摘要：
背景：深静脉血栓（DVT）是威胁人类健康和经济发展的严重公共卫生问题。目前,不同民族个体DVT患病率的差异，高海拔地区的居民,那些吃任何特殊饮食的人是未知的。因此,我们旨在阐明高原地区住院患者DVT的患病率和相关危险因素.
方法：研究对象为青海省三家三级甲等医院住院患者,中国,2020年1月至10月。人口统计，临床,入院时收集实验室数据，并进行了双侧下肢的超声检查。出院时记录住院时间。
结果：共纳入3432例患者，其中159例（4.60%）诊断为DVT。年龄>50岁(OR=2.434,95%CI:1.521-3.894252,P<0.001),居住高度≥3000米（OR=2.346，95%CI：1.239-4.440，P=0.009），D-二聚体水平≥0.5mg/L(OR=2.211,95%CI:1.547-3.161,P<0.001),合并症的存在（OR=1.904，95％CI：1.386-2.705，P<0.001），静脉曲张病史(OR=1.990,95%CI:0.959-4.128,P=0.045),和目前的药物治疗(OR=2.484,95%CI:1.778-3.471,P<0.001)被确定为这些高原地区DVT的危险因素。
结论：高原地区住院患者DVT的患病率为4.60%。我们建议考虑个性化风险分层(年龄>50岁，居住高度≥3000m，静脉曲张病史,D-二聚体水平≥0.5mg/L,目前的药物,和合并症）入院时的患者。
方法：研究对象为青海省三家三级甲等医院住院患者,中国,2020年1月至10月。人口统计，临床,入院时收集实验室数据，并进行了双侧下肢的超声检查。出院时记录住院时间。
结果：共纳入3432例患者，其中159例（4.60%）诊断为DVT。年龄>50岁(OR=2.434,95%CI:1.521-3.894252,P<0.001),居住高度≥3000米（OR=2.346，95%CI：1.239-4.440，P=0.009），D-二聚体水平≥0.5mg/L(OR=2.211,95%CI:1.547-3.161,P<0.001),合并症的存在（OR=1.904，95％CI：1.386-2.705，P<0.001），静脉曲张病史(OR=1.990,95%CI:0.959-4.128,P=0.045),和目前的药物治疗(OR=2.484,95%CI:1.778-3.471,P<0.001)被确定为这些高原地区DVT的危险因素。
结论：高原地区住院患者DVT的患病率为4.60%。我们建议考虑个性化风险分层(年龄>50岁，居住高度≥3000m，静脉曲张病史,D-二聚体水平≥0.5mg/L,目前的药物,和合并症）入院时的患者。
