Abstract：
Breast reconstructive surgery has evolved significantly over the years. One of the recent advancements is the use of prepectoral implants in combination with synthetic and biological material as a natural and effective coverage. To date, there is little published data on breast reconstruction using acellular bovine pericardium matrix and most concern submuscular breast reconstruction. This study aimed to describe the multicentric-multisurgeon experience in performing direct to implant (DTI) prepectoral breast reconstructions using acellular bovine pericardium matrix (ABPM) pocket. A retrospective multicentric data collection of the all the immediate prepectoral breast reconstructions using acellular bovine pericardium was carried out by the authors. Surgical data including type of mastectomy, axillary surgery, type and size of implant, size of ABPM, duration of surgery were collected for each patient. Postoperative data including adjuvant treatments, complications, necessity to perform other interventions, patient\'s satisfaction were collected. Cosmetic results were also evaluated by 7 different observers at minimum 1 year follow-up. A total of 65 breast reconstruction were included in the study. Mean follow up was 21.3 months. Average surgical time was 1,42 hours. Minor complications occurred in 4 breasts; major complications occurred in 2 breasts. After 6 months follow-up, 7 patients underwent fat grafting to correct any rippling and /or wrinkling. Breast aesthetic and patients reported outcomes were satisfactory. Not significant capsular contracture was noted at the follow up control. To date, this is the largest study about prepectoral breast reconstruction with ABPM. On the basis of our results, prepectoral breast reconstruction ABPM assisted is a reliable, safe and suitable option providing good patient satisfaction outcomes.
摘要：
多年来，乳房重建手术取得了显着进展。最近的进步之一是将胸前植入物与合成和生物材料结合使用作为自然有效的覆盖范围。迄今为止,关于使用无细胞牛心包基质进行乳房重建的已发表数据很少，而最关注的是肌肉下乳房重建。这项研究旨在描述使用无细胞牛心包膜基质（ABPM）口袋进行直接植入（DTI）胸前乳房重建的多中心多外科医生经验。作者对使用无细胞牛心包进行的所有即时胸前乳房重建的回顾性多中心数据收集。手术数据包括乳房切除术的类型，腋窝手术,植入物的类型和大小，ABPM的大小，收集每位患者的手术持续时间.术后数据，包括辅助治疗，并发症,进行其他干预的必要性，收集患者的满意度。在至少1年的随访中,还由7名不同的观察者评价了美容结果。该研究共包括65例乳房重建。平均随访21.3个月。平均手术时间为1,42小时。4例乳房发生轻微并发症；2例乳房发生主要并发症。经过6个月的随访，7名患者接受脂肪移植以纠正任何波纹和/或皱纹。乳房美学和患者报告的结果令人满意。在随访对照中没有发现明显的包膜挛缩。迄今为止,这是关于ABPM胸前乳房再造的最大研究。根据我们的结果，胸前乳房重建ABPM是一种可靠的，安全和合适的选择，提供良好的患者满意度结果。
