关键词: Biomedical engineering Biopolymers Chitosan hydrogel Circular economy Food technology

Mesh : Chitosan / chemistry Hydrogels / chemistry Humans Biomedical Engineering / methods trends Biocompatible Materials / chemistry Drug Delivery Systems Animals Green Chemistry Technology / methods

来  源:   DOI:10.1016/j.ijbiomac.2024.133823

Abstract:
Eco-friendly materials have emerged in biomedical engineering, driving major advances in chitosan-based hydrogels. These hydrogels offer a promising green alternative to conventional polymers due to their non-toxicity, biodegradability, biocompatibility, environmental friendliness, affordability, and easy accessibility. Known for their remarkable properties such as drug encapsulation, delivery capabilities, biosensing, functional scaffolding, and antimicrobial behavior, chitosan hydrogels are at the forefront of biomedical research. This paper explores the fabrication and modification methods of chitosan hydrogels for diverse applications, highlighting their role in advancing climate-neutral healthcare technologies. It reviews significant scientific advancements and trends chitosan hydrogels focusing on cancer diagnosis, drug delivery, and wound care. Additionally, it addresses current challenges and green synthesis practices that support a circular economy, enhancing biomedical sustainability. By providing an in-depth analysis of the latest evidence on climate-neutral management, this review aims to facilitate informed decision-making and foster the development of sustainable strategies leveraging chitosan hydrogel technology. The insights from this comprehensive examination are pivotal for steering future research and applications in sustainable biomedical solutions.
摘要:
生物医学工程中出现了环保材料,推动壳聚糖基水凝胶的重大进展。这些水凝胶由于其无毒性,为传统聚合物提供了一种有前途的绿色替代品,生物降解性,生物相容性,环境友好,负担能力,和容易获得。以其非凡的特性而闻名,如药物封装,交付能力,生物传感,功能性脚手架,和抗菌行为,壳聚糖水凝胶是生物医学研究的前沿。本文探讨了用于多种应用的壳聚糖水凝胶的制备和改性方法。强调他们在推进气候中性医疗技术方面的作用。它回顾了重要的科学进步和趋势壳聚糖水凝胶专注于癌症诊断,药物输送,和伤口护理。此外,它解决了当前的挑战和支持循环经济的绿色综合实践,提高生物医学的可持续性。通过对气候中立管理的最新证据进行深入分析,这篇综述旨在促进明智的决策,并促进利用壳聚糖水凝胶技术的可持续战略的发展。这项全面检查的见解对于指导未来可持续生物医学解决方案的研究和应用至关重要。
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