Abstract：
This study aimed to explore the effects of different lipid sources on the performance, blood lipid parameters, immune system activity, and the expression of TNFα and TLR4 genes in broiler chickens. A total of 500 one-day-old male chicks of the ROSS 308 commercial strain were allocated into four treatment groups with five replicates each (each replicate comprised of 25 chickens), following a randomized design. The treatments were as follows: (1) a diet incorporating palm oil (PO, a source of saturated fatty acids); (2) a diet incorporating flaxseed oil (FO, a source of omega-3); (3) a diet incorporating soybean oil (SO, a source of omega-6); and (4) a diet incorporating olive oil (OO, a source of omega-9). According to the findings, the broiler chickens exhibited a significant increase in body weight gain (BWG) throughout the study when their diet consisted of unsaturated oils, as opposed to a diet including PO. Conversely, the feed conversion ratio (FCR) significantly decreased (P<0.01). The treatment with FO resulted in the highest percentage of lymphocytes and antibody titers against Newcastle and Gumboro diseases, showing a significant difference compared to the treatment with PO (P<0.01). Moreover, the relative expression of TNFα and TLR4 genes was the lowest following the FO treatment, indicating a significant decrease compared to the treatment with PO. Overall, the present findings demonstrated that incorporating omega-3 fatty acids into the diet was more effective in enhancing the growth performance, immune system, and health of broiler chickens.
摘要：
本研究旨在探讨不同脂源对生产性能的影响,血脂参数，免疫系统活动，以及TNFα和TLR4基因在肉鸡中的表达。将ROSS308商业品系的总共500只一天大的雄性小鸡分配到四个处理组中，每个处理组重复五个（每个重复包括25只鸡）。按照随机设计。处理方法如下：(1)掺入棕榈油的饮食(PO，饱和脂肪酸的来源)；(2)掺入亚麻籽油的饮食(FO，omega-3的来源)；(3)掺入大豆油的饮食(SO，omega-6的来源)；和(4)含有橄榄油的饮食(OO，omega-9的来源）。根据调查结果,在整个研究过程中，当肉鸡的饮食由不饱和油组成时，肉鸡的体重增加（BWG）显着增加，与包括PO在内的饮食相反。相反，饲料转化率(FCR)显著降低(P<0.01)。用FO治疗导致针对新城疫和Gumboro疾病的淋巴细胞和抗体滴度百分比最高，与PO处理相比，差异有统计学意义（P<0.01）。此外，FO处理后，TNFα和TLR4基因的相对表达量最低，表明与用PO处理相比显著降低。总的来说,目前的研究结果表明，在饮食中加入omega-3脂肪酸更有效地提高了生长性能，免疫系统,和健康的肉鸡。
