Abstract：
Sepsis is still one of the most common causes of death of animals and humans. It is marked by an aberrant immune response to infection, resulting in extensive inflammation, organ dysfunction, and, in severe instances, organ failure. Recognizable symptoms and markers of sepsis encompass substantial elevations in body temperature, respiratory rate, hemoglobin levels, and alterations in immune cell counts, including neutrophils, monocytes, and basophils, along with increases in certain acute-phase proteins. In contrast to human medicine, veterinarians must take into account some species differences. This article provides a comprehensive overview of changes in the immune system during sepsis, placing particular emphasis on species variations and exploring potential future drugs and interventions. Hence, understanding the intricate balance of the immune responses during sepsis is crucial to develop effective treatments and interventions to improve the chances of recovery in animals suffering from this serious condition.
摘要：
脓毒症仍然是动物和人类死亡的最常见原因之一。它的特点是对感染的异常免疫反应，导致广泛的炎症，器官功能障碍,and,在严重的情况下，器官衰竭可识别的败血症症状和标志物包括体温大幅升高，呼吸频率,血红蛋白水平，和免疫细胞计数的改变，包括中性粒细胞,单核细胞,和嗜碱性粒细胞,随着某些急性期蛋白的增加。与人类医学相比，兽医必须考虑一些物种差异。本文对脓毒症期间免疫系统的变化进行了全面的概述，特别强调物种变异，探索潜在的未来药物和干预措施。因此，了解脓毒症期间免疫反应的复杂平衡对于开发有效的治疗和干预措施以提高患有这种严重疾病的动物的康复机会至关重要。
