Abstract:
Normocalcemic primary hyperparathyroidism (NPHPT), a variant of primary hyperparathyroidism (PHPT) characterized by persistently elevated parathyroid hormone (PTH) levels and normal serum calcium, has gained recognition as a substantial subset of PHPT cases. Despite its increasing prevalence, the precise pathophysiology and natural progression of NPHPT remain enigmatic. This in-depth literature review explores recent advancements in our understanding of NPHPT, encompassing pathophysiology, clinical presentation, diagnostic approaches, medical and surgical management options. By synthesizing this wealth of information, this review aims to contribute to a more nuanced and informed approach to the treatment of patients grappling with NPHPT. As our understanding of the condition continues to evolve, the knowledge gathered from this review has the potential to significantly enhance the quality of care and outcomes for individuals afflicted with NPHPT, ultimately improving their overall well-being and prognosis.
摘要:
正常血钙原发性甲状旁腺功能亢进(NPHPT),原发性甲状旁腺功能亢进(PHPT)的一种变体,其特征是持续升高的甲状旁腺激素(PTH)水平和正常的血清钙,已被确认为PHPT病例的重要子集。尽管患病率越来越高,NPHPT的精确病理生理学和自然进展仍然是神秘的。这篇深入的文献综述探讨了我们对NPHPT的理解的最新进展,包括病理生理学,临床表现,诊断方法,医疗和外科管理选择。通过综合这些丰富的信息,本综述旨在为NPHPT患者的治疗提供更细致和更知情的方法.随着我们对病情的理解不断发展,从这篇综述中收集的知识有可能显著提高NPHPT患者的护理质量和结果,最终改善他们的整体健康状况和预后。