PDF(Pubmed)
Abstract：
The purpose of this study was to evaluate a resin based pit and fissure sealant containing 45S5 bioactive glass (BAG) by examining its ion release, pH variation, and apatite-forming properties. To prepare the experimental materials, 45S5 BAG, used as a filler, was incorporated into the light curable resin matrix at concentrations of 0 (control), 12.5, 37.5, and 50.0 wt.%. Ion release, pH variation, and apatite formation (Raman spectrometer and scanning electron microscopy-energy-dispersive X-ray spectrometry measurements) were performed. While no ions were released from the control group, the experimental groups containing 45S5 BAG showed an increased release of Ca and P ions with increasing amounts of 45S5 BAG (p < 0.05). The pH of the experimental group remained high and was significantly different from the control group (p < 0.05). Unlike the control group, it was confirmed that the apatite peak was formed in the 50.0 wt.% BAG group for 90 days, and the apatite layer consisting of Ca and P was deposited on the surface. Thus, a resin based pit and fissure sealant containing 45S5 BAG is a promising material for preventing secondary caries by releasing ions and forming apatite.
摘要：
这项研究的目的是通过检查其离子释放来评估含有45S5生物活性玻璃（BAG）的树脂基凹陷和裂缝密封剂，pH变化,和磷灰石形成性能。准备实验材料,45S5袋,用作填料，以0的浓度掺入到光固化树脂基质中（对照），12.5、37.5和50.0wt。%.离子释放,pH变化,和磷灰石的形成（拉曼光谱仪和扫描电子显微镜-能量色散X射线光谱法测量）进行。虽然对照组没有释放离子，含45S5BAG的实验组显示随着45S5BAG量的增加，Ca和P离子的释放增加（p<0.05）。实验组的pH保持较高，与对照组差异显着（p<0.05）。与对照组不同，证实磷灰石峰形成于50.0wt。%BAG组90天,表面沉积了由Ca和P组成的磷灰石层。因此，含有45S5BAG的树脂基凹陷和裂缝密封剂是一种有前途的材料，可通过释放离子和形成磷灰石来防止二次龋齿。
