PDF(Pubmed)
Abstract：
Ecosystems are negatively impacted by pharmaceutical-contaminated water in different ways. In this work, a new biosorbent obtained by immobilizing Lactococcus lactis in a calcium alginate matrix was developed for the removal of pharmaceuticals from aqueous solutions. Ethacridine lactate (EL) was selected as the target drug. Lactococcus Lactis biomass was chosen for the biosorbent synthesis for two reasons: (i) the microbial biomass used in the food industry allows the development of a low-cost biosorbent from available and renewable materials, and (ii) there is no literature mentioning the use of Lactococcus Lactis biomass immobilized in natural polymers as a biosorbent for the removal of pharmaceuticals. The characterization of the synthesized biosorbent named 5% LLA was performed by scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR) analysis. Additionally, particle size and the point of zero charge were established. Batch biosorption investigations showed that using 5% LLA at an initial pH of 3.0 and a biosorbent dose of 2 g/L resulted in up to 80% EL removal efficiency for all EL initial concentrations (20-60 mg/L). Four equilibrium isotherms, given in the order of Redlich-Peterson > Freundlich > Hill > Temkin, are particularly relevant for describing the experimental data for EL biosorption on the 5% LLA biosorbent using correlation coefficient values. Kinetic parameters were determined using kinetic models such as pseudo-first-order, pseudo-second-order, Elovich, Avrami and Weber-Morris. The pseudo-second-order kinetics model provides the greatest fit among the evaluated equations, with correlation coefficients greater than 0.99. According to the study\'s findings, the developed biocomposite is a potentially useful material for the removal of pharmaceuticals from aqueous matrices.
摘要：
生态系统以不同的方式受到药物污染的水的负面影响。在这项工作中,开发了一种通过将乳酸乳球菌固定在海藻酸钙基质中而获得的新型生物吸附剂，用于从水溶液中去除药物。选择乳酸依沙吖啶(EL)作为目标药物。选择乳酸乳球菌生物质进行生物吸附剂合成有两个原因：（i）食品工业中使用的微生物生物质允许从可用和可再生材料中开发低成本的生物吸附剂，和(ii)没有文献提到固定在天然聚合物中的乳酸乳球菌生物质作为用于去除药物的生物吸附剂的用途。通过扫描电子显微镜（SEM）和傅立叶变换红外光谱（FTIR）分析对合成的5％LLA生物吸附剂进行表征。此外,建立了颗粒尺寸和零电荷点。批量生物吸附研究表明，在初始pH值为3.0和2g/L的生物吸附剂剂量下使用5％LLA，对于所有EL初始浓度（20-60mg/L），EL的去除效率高达80％。四个平衡等温线，按照Redlich-Peterson>Freundlich>Hill>Temkin的顺序给出，与使用相关系数值描述在5％LLA生物吸附剂上的EL生物吸附的实验数据特别相关。动力学参数是使用动力学模型确定的，如伪一级，伪二阶，埃洛维奇,Avrami和Weber-Morris.伪二阶动力学模型在评估的方程中提供了最大的拟合，相关系数大于0.99。根据研究结果,开发的生物复合材料是从水性基质中去除药物的潜在有用材料。
