TLR 激动剂在急性淋巴细胞白血病中改变 NK 细胞活化并增加其细胞毒性。
关键词: IFN-γ NKG2D NKp44 acute lymphoblastic leukemia cytotoxicity natural killer cells toll-like receptors
Mesh : Humans Killer Cells, Natural / immunology drug effects metabolism Precursor Cell Lymphoblastic Leukemia-Lymphoma / immunology drug therapy pathology Poly I-C / pharmacology Lymphocyte Activation / drug effects immunology Imiquimod / pharmacology Toll-Like Receptors / metabolism agonists Child Oligodeoxyribonucleotides / pharmacology Cytokines / metabolism Female Interferon-gamma / metabolism Male Imidazoles / pharmacology Cytotoxicity, Immunologic / drug effects Child, Preschool Toll-Like Receptor Agonists
来 源:
DOI:10.3390/ijms25137500
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