PDF(Pubmed)
Abstract：
Obesity is a worldwide increasing concern. Although in adults this is easily estimated with the body mass index, in children, who are constantly growing and whose bodies are changing, the reference points to assess weight status are age and gender, and need corroboration with complementary data, making their quantification highly difficult. The present review explores the interaction spectrum of oxidative stress, selenium status, and obesity in children and adolescents. Any factor related to oxidative stress that triggers obesity and, conversely, obesity that induces oxidative stress are part of a vicious circle, a complex chain of mechanisms that derive from each other and reinforce each other with serious health consequences. Selenium and its compounds exhibit key antioxidant activity and also have a significant role in the nutritional evaluation of obese children. The balance of selenium intake, retention, and metabolism emerges as a vital aspect of health, reflecting the complex interactions between diet, oxidative stress, and obesity. Understanding whether selenium status is a contributor to or a consequence of obesity could inform nutritional interventions and public health strategies aimed at preventing and managing obesity from an early age.
摘要：
肥胖是全世界日益关注的问题。尽管在成年人中，这很容易通过体重指数估算，在儿童中，他们不断成长，他们的身体在变化，评估体重状况的参考点是年龄和性别，需要补充数据的佐证，使他们的量化变得非常困难。本综述探讨了氧化应激的相互作用谱，硒状态，儿童和青少年肥胖。任何与氧化应激相关的因素都会引发肥胖，相反,引起氧化应激的肥胖是恶性循环的一部分，一个复杂的机制链，这些机制相互衍生，相互加强，造成严重的健康后果。硒及其化合物具有关键的抗氧化活性，在肥胖儿童的营养评估中也具有重要作用。硒摄入量的平衡，保留,新陈代谢是健康的一个重要方面，反映了饮食之间复杂的相互作用，氧化应激，和肥胖。了解硒的状态是否是肥胖的原因或后果，可以为旨在预防和管理早期肥胖的营养干预和公共卫生策略提供信息。
