PDF(Pubmed)
Abstract：
Monitoring the tumor margins of basal cell carcinomas is still a challenge in everyday clinical practice. Usually, the clinical margins of the tumor are marked by the naked eye or, even better, with dermoscopy before surgery and then examined in detail after the operation using histological examination. In order to achieve tumor freedom, several surgical steps are sometimes necessary, meaning that patients spend longer periods in hospital and the healthcare system is burdened more as a result. One way to improve this is the one-stop shop method, which requires precise diagnostics and margin marking before and during surgery so that tumor freedom can be achieved after just one surgery. For this reason, the current status of the diagnosis and treatment of basal cell carcinomas before and after surgery is to be examined following extensive literature research using devices and methods that have already been tested in order to determine how a simplified process of tumor margin control of basal cell carcinomas can be made possible both in vivo and ex vivo.
摘要：
在日常临床实践中，监测基底细胞癌的肿瘤边缘仍然是一个挑战。通常,肿瘤的临床边缘用肉眼标记，甚至更好，手术前进行皮肤镜检查，然后在手术后使用组织学检查进行详细检查。为了实现肿瘤的自由，有时需要几个手术步骤，这意味着患者在医院呆的时间更长，因此医疗保健系统负担更多。改善这种情况的一种方法是一站式方法，这需要在手术前和手术期间进行精确的诊断和边缘标记，以便仅在一次手术后即可实现肿瘤自由。出于这个原因,手术前后基底细胞癌的诊断和治疗的现状将在广泛的文献研究后进行检查，使用已经过测试的设备和方法，以确定如何简化基底细胞癌的肿瘤边缘控制过程可以在体内和体外成为可能。
