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Abstract：
Background: This study aims to investigate the postoperative improvement of paralysis, fusion rate and risk factors for kyphosis progression in adults affected with spinal caries. Methods: Overall, 134 patients with spinal caries from the thoracic to lumbar spine from 1992 to 2021 were included in this study. Data concerning the affected level (thoracic, thoracolumbar, lumbar, and lumbosacral), bone fusion rate, and progression of the postoperative local kyphosis angle were collected. The risk factors for the progression of local kyphosis angle after anterior spinal fixation (ASF) were determined using linear regression analysis. Results: Preoperatively, the degree of spinal cord paralysis was D and E on Frankel classification. Improvement of paralysis was good with surgery, especially from C, D. The overall bone fusion rate was 83.2%. The only factor influencing the progression of local kyphosis angle after ASF was the level of the affected vertebra. Progression of kyphosis angle after ASF was very advanced in the thoracolumbar transition area. Conclusions: Surgical improvement in paraplegia and the fusion rate of ASF with only grafted bone was good. However, in patients affected in the thoracolumbar spine region, posterior instrumentation is desirable because of local kyphosis progression risk after surgery.
摘要：
背景:本研究旨在探讨瘫痪患者术后的改善情况,受脊柱龋齿影响的成人脊柱后凸的融合率和危险因素。方法：总体，这项研究包括了1992年至2021年从胸椎到腰椎的134例龋齿患者。有关受影响水平的数据(胸部，胸腰椎,腰椎,和腰骶)，骨融合率,收集术后局部后凸角度的进展。使用线性回归分析确定前路脊柱固定术（ASF）后局部后凸角进展的危险因素。结果：术前，脊髓麻痹程度Frankel分级为D级和E级。手术改善了瘫痪，尤其是C,D.总体骨融合率为83.2%。影响ASF后局部后凸角度进展的唯一因素是受影响椎骨的水平。ASF后脊柱后凸角度的进展在胸腰椎过渡区非常先进。结论：截瘫的手术改善和仅移植骨的ASF融合率良好。然而,在胸腰段脊柱受累的患者中，由于手术后局部后凸的进展风险,因此需要后路器械.
