PDF(Pubmed)
Abstract：
Background/Objective: Clostridioides difficile infection (CDI) is a common healthcare-associated ailment, presenting major health and economic challenges, especially for the elderly. Despite its prevalence, comprehensive data about CDI\'s impact on the elderly are limited. Methods: This study used the Global Burden of Disease Study 2019 data to analyze CDI trends from 2000 to 2019, considering factors like sex, region, and sociodemographic index (SDI). Results: This study revealed that CDI caused approximately 18,181 deaths and 252,709 disability-adjusted life years (DALYs) among the elderly worldwide. The Americas showed the highest CDI burden, while the Eastern Mediterranean saw the steepest rate increase from 2000 to 2019. Regions with a high SDI also displayed substantial CDI impact. Conclusions: The escalating burden of CDI in the elderly, especially in high-SDI areas and the Americas, emphasizes an urgent need for targeted public health strategies.
摘要：
背景/目的：艰难梭菌感染（CDI）是一种常见的医疗保健相关疾病，面临重大的健康和经济挑战，尤其是老年人。尽管流行,关于CDI对老年人影响的综合数据有限。方法：本研究使用全球疾病负担研究2019年的数据，分析了2000年至2019年的CDI趋势，考虑了性别、区域,和社会人口统计学指数(SDI)。结果：这项研究显示，CDI在全球老年人中造成约18,181例死亡和252,709个残疾调整寿命年（DALYs）。美洲显示出最高的CDI负担，而从2000年到2019年，东地中海的增长率最快。具有高SDI的区域也显示出显著的CDI影响。结论：老年人CDI负担不断加重，特别是在高SDI地区和美洲，强调迫切需要有针对性的公共卫生战略。
