PDF(Pubmed)
Abstract：
Quercetin, a bioactive plant flavonoid, is an antioxidant, and as such it exhibits numerous beneficial properties including anti-inflammatory, antiallergic, antibacterial and antiviral activity. It occurs naturally in fruit and vegetables such as apples, blueberries, cranberries, lettuce, and is present in plant waste such as onion peel or grape pomace which constitute good sources of quercetin for technological or pharmaceutical purposes. The presented study focuses on the role of quercetin in prevention and treatment of dermatological diseases analyzing its effect at a molecular level, its signal transduction and metabolism. Presented aspects of quercetin potential for skin treatment include protection against aging and UV radiation, stimulation of wound healing, reduction in melanogenesis, and prevention of skin oxidation. The article discusses quercetin sources (plant waste products included), methods of its medical administration, and perspectives for its further use in dermatology and diet therapy.
摘要：
槲皮素,一种生物活性植物类黄酮，是一种抗氧化剂,因此，它表现出许多有益的特性，包括抗炎，抗过敏,抗菌和抗病毒活性。它天然存在于水果和蔬菜如苹果中，蓝莓,小红莓,生菜,并且存在于植物废物中，例如洋葱皮或葡萄果渣，它们构成了用于技术或药物目的的槲皮素的良好来源。本研究的重点是槲皮素在皮肤科疾病的预防和治疗中的作用，分析其在分子水平上的作用，它的信号转导和代谢。槲皮素潜在的皮肤治疗方面包括防止老化和紫外线辐射，刺激伤口愈合，减少黑色素生成，和预防皮肤氧化。本文讨论了槲皮素的来源(包括植物废物)，其医疗管理方法，以及其在皮肤病学和饮食疗法中进一步使用的前景。
